Everlight Usa, Inc.

Rung-Tian Suen

Yu-Liang Liu

Chi-Hsiang Yao

Ying-Chi Chiu

The present invention provides a compound of the following formula (I): wherein Ris methyl or 4-aminobutyl, which may be acylated; X is phenyl or substituted phenyl; W is an esterified group removable by hydrogenolysis. Also disclosed is the preparation method and the application of formula (I) compound.

N-(4-oxo-butanoic acid) -L-amino acid-ester derivatives and methods of preparation thereof

A method for preparing a prostaglandin F-type compound. Also disclosed is an intermediate of the following formula (II) compound wherein R', X and A have the same meaning as given in the specification.

Method and intermediate for preparing a prostaglandin F-type compound

The present invention discloses a method for preparing a prostaglandin E-type compound, in which prostaglandin F-type compound is used as an initiator to generate novel derivative of prostaglandin F-type compound through a silylation reaction, and eventually a prostaglandin E-type compound is obtained through an oxidation and a desilylation reaction.

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Taipei, Taiwan

Rung-Tian Suen