Pharmacia Ab

Rune Bjorkman

Rolf E Axen

Goran L Kaj

A device for handling porous solid matrixes (16) in analytic determinations of the type comprising at least one reaction step, which is performed in the very matrixes by absorption of a liquid phase therein, comprises a holder (1) and at least one matrix carrier (2), each of which can retain a matrix (16) while at the same time permitting liquid which surrounds the matrix carrier to substantially unobstructedly be absorbed by the matrix. The holder (1) is provided with at least one gripping body (11) projecting therefrom, each of which can detachably carry a corresponding matrix carrier (2), and at least one squeezing body (11), each of which can be pressed against the porous matrix for squeezing out liquid from the same. An analysis apparatus comprises such a handling device, the holder (1) of which is carried by a driving mechanism in the apparatus, which driving mechanism has driving means for both horizontal and vertical displacement of the holder (1), so that matrix carriers (2) carried by the same can be moved horizontally between adjacent liquid containers (29, 29', 30) and vertically down into and up from selected liquid containers.

Device for handling porous matrixes and an analysis apparatus comprising

Method and device for biospecific affinity reactions

Module holder for test tubes

The invention relates to an apparatus for carrying out analyses comprising at least one incubation step and at least one separation step for separating a liquid phase from a phase, which is insoluble in said liquid phase. The apparatus comprises a plurality of reaction vessels (2), making it possible to simultaneously carry out similar working sequences with reaction mixtures in the separate reaction vessels, each of which has a porous bottom (3) connected to a separate chamber (8), the reaction vessels being able to retain the reaction mixture during the incubation steps. According to the invention, there is provided a pressure regulating system, which creates a higher relative pressure in the chambers (8) than in the reaction vessels (2). This pressure difference prevents leakage from the reaction vessels to the chambers.

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Balinge, Sweden

Rune Bjorkman