Genentech, Inc.

Other

Genetech, Inc.

Natrogen Therapeutics International, Inc.

Natrogen Therapeutics, Inc.

Ruihuan Chen

Zemin Zhang

P Mickey Williams

Thomas J Wu

Heidi S Phillips

Victoria Smith

Kenneth J Hillan

Paul Polakis

Susan D Spencer

Gretchen Frantz

Hartmut Koeppen

Belinda Cairns

Longgui Wang

Xiaomei Liu

Thomas D Wu

Susan D Spenser

Harmut Koeppen

Anan Chuntharapai

Chie Sakanaka

Simon K Mencher

Xiao Mei Liu

Allen Tsao

Chae Janeka Reed

Mickey P Williams

Heidi Phillips

Kartmut Koeppen

The present invention is directed to compositions of matter useful for the diagnosis and treatment of tumor in mammals and to methods of using those compositions of matter for the same.

Methods for the treatment of tumors expressing TAT123 or naturally occurring variants thereof

Compositions and methods for the diagnosis and treatment of tumor

The present invention is directed to a method for treating inflammatory arthritis in a mammal. The method typically comprises administering to an animal a therapeutically effective amount of at least one compound selected from indigo, isoindigo, indirubin or derivatives thereof, such as NATURA-&#x3b1; or NATURA. The present invention is further directed to pharmaceutical compositions that include a therapeutically effective amount of at least one compound of the invention, an anti-inflammatory arthritis agent and a pharmaceutically acceptable carrier.

Method of treating inflammatory arthritis

Antibody compositions for the diagnosis and treatment of tumor

Anti-TAT188 antibodies

Antibodies specific for TAT285-1

A compound called NATURA, which is a derivative of Isoindigo is useful in aiding the general health of a patient and specifically is beneficial in preventing or treating cancer. This compound and other related Isoindigo, Indigo and Indirubin derivatives are designed such that the bioactivity or bioavailability of the compound is increased. Methods of synthesizing these derivatives is also taught. In addition, pharmaceutical compositions that include a therapeutically effective amount of at least one of these derivatives and a pharmaceutically acceptable carrier. A method for the use of these pharmaceutical compositions and compounds is taught, wherein a therapeutically effective amount is administered to an animal having solid tumor cancer. The pharmaceutical composition or compound can be re-administered to the animal until a desired treatment or result is accomplished.

Derivatives of isoindigo, indigo and indirubin and methods of treating cancer

A compound called NATURA, which is a derivative of Isoindigo is useful in aiding the general health of a patient and specifically is beneficial in preventing or treating cancer. This compound and other related Isoindigo, Indigo and Indirubin derivatives are designed such that the bioactivity or bioavailability of the compound is increased. Also, pharmaceutical compositions that include a therapeutically effective amount of at least one of these derivatives and a pharmaceutically acceptable carrier. A method for the use of these pharmaceutical compositions and compounds is taught, wherein a therapeutically effective amount is administered to an animal. The pharmaceutical composition or compound can be re-administered to the animal until a desired treatment or result is accomplished.

Derivative of isoindigo, indigo and indirubin for the treatment of cancer

Growing community of inventors

Foster City, CA, United States of America

Ruihuan Chen