Wuhan Yzy Biopharma Co., Ltd.

Hon Hai Precision Industry Co., Ltd.

Hongfujin Precision Industry (wuhan) Co., Ltd.

Wuhan University

Wuhan Wei Newtech Medical Co. , Ltd.

Rui Wang

Jing Zhang

Pengfei Zhou

Xiang Zhou

Lingli Hu

Kesu Fan

Li-Fu Xu

Wen Zhang

Zhi-Jiang Yao

Fei Li

Xiaoyan Liu

Hui Zhong

Sisi Fu

Changhui Yu

Yisong Wang

Chongxin Tao

Lingkui Meng

Changlu Cui

Beibei Yang

Yizhuo Meng

Ziwen Gao

Rui Li

Linyi Li

Xiang Wei

Shuai Xu

Huixin Dai

Yun Sun

Jing Fang

A method of storing remote sensing big data in a Hbase database. The method includes: obtaining a remote sensing image, and pre-cropping the remote sensing image based on a Google S2 algorithm; selecting a grid level based on a resolution of the remote sensing image; demarcating a coverage scope of the remote sensing image; calculating grids covered within the coverage scope; cropping the remote sensing image according to the grids, to yield a plurality of image blocks, and serializing the plurality of image blocks; establishing an Hbase table; establishing a table storage model containing RowKey, and calculating the RowKey according to attributes of an image block; and integrating data structure of multi-source remote sensing image data according to attribute expression of a zoned remote sensing image in a plurality of dimensions, and storing serialized image blocks in an Hbase database according to the RowKey.

Method of storing remote sensing big data in Hbase database

Provided are compositions and methods for preparing a cell suitable for producing a bispecific antibody. A plurality of eukaryotic cells are incubated with an agent under conditions to allow the cells to arrest at G1/S phase. The agent is then removed from the cells and the cells are transfected with a first vector comprising a sequence encoding a first monovalent antigen-binding unit having specificity to a first antigen and a second vector comprising a sequence encoding a second monovalent antigen-binding unit having specificity to a second antigen. A cell is identified from the plurality of cells that expresses both the first and the second antigen-binding units.

Preparation and selection of cells for producing bispecific antibodies

The present invention provides a bispecific antibody. The bispecific antibody provided by the present invention comprises a single-chain unit and a monovalent unit, wherein the single-chain unit has a specific binding capability against a surface antigen CD3 of an immune cell; the monovalent unit has a specific binding capability against a surface antigen HER2 of a tumor cell; the single-chain unit comprises a single-chain variable fragment ScFv fused with an Fc fragment; and the monovalent unit comprises a light chain and heavy chain pair. The present invention also provides a preparation method of the bispecific antibody and pharmaceutical use of these antibodies.

Construction and application of bispecific antibody HER2xCD3

An electronic device comprises a cooler comprises a plurality of first locking members, a backboard defining pluralities of first and second positioning holes, and a circuit board. The backboard is attached to the cooler through the first locking members engaged with the second positioning holes. A first mounting member and a second mounting member are adapted to receive the heat generating component. The first mounting member defines a plurality of locking holes. The first positioning holes are among the second positioning holes. The second mounting member receives the heat generating component, the circuit board is between the second mounting member and the backboard, the first mounting member is secured to the circuit board; when the first mounting member receives the heat generating component, the circuit board is between the first mounting member and the backboard, the first mounting member is secured to the backboard.

Electronic device with cooler

Growing community of inventors

Wuhan, China

Rui Wang