Roche Diagnostics Operations, Inc.

Roche Diagnostics Gmbh

F. Hoffmann-la Roche Ag

Ruediger Laubender

Friedemann Krause

Albert Geiger

Daniel Intelmann

Kirill Tarasov

Julian Michely

Andreas Reichert

A computer-implemented method for determining failures in laboratory equipment comprising: a) receiving a desired probability of false rejection (P̌) and a desired error detection rate (Ě), such as a desired probability of error detection (P̌), relating to one or more QC levels (J) of quality control (QC) samples to be processed by the equipment; b) setting a number of runs (R) to one; c) calculating an error detection rate (Ê) based at least partially on R; d) determining if Êis below Ě, and if so: increase R by one, and repeat steps c) to d), and if not: define a rule for determining failures in the laboratory equipment based, at least partially, on R; e) receiving or collecting standardized QC results; f) applying the rule defined in step d) to the standardized QC results; g) determining failures in the equipment, if the standardized QC results comply with the rule.

Computerized method and laboratory equipment for fast detection of failure in laboratory equipment

A method for monitoring an analyzer including a liquid chromatography device (LC) having at least two liquid chromatography (LC) streams, the method including continuously monitoring one or more parameters in measurement data of samples in each of the at least two LC streams, the one or more parameters being independent of an analyte concentration of the respective sample, determining if the one or more monitored parameters show an expected behavior and triggering a response upon detection that the one or more monitored parameters deviate from the expected behavior.

Techniques for monitoring an analyzer including multiple liquid chromatography streams

Growing community of inventors

Pullach im Isartal, Germany

Ruediger Laubender