Schering Corporation

Rudolph O Neri

John G Topliss

Robert J Spiegel

A method of treating gynecomastia in noncastrated patients being treated with an antiandrogen for androgen-dependent diseases such as benign prostatic hypertrophy, who are in need of such treating comprising administering to such patients therapeutically effective amounts of an antiandrogen, e.g., flutamide, in association with an antiestrogen, e.g., Tamoxifen, or an aromatase inhibitor such as 4-hydroxyadrostenedione is disclosed.

Method of treating gynecomastia

A pharmaceutical preparation comprising flutamide, useful in the treatment of prostatic carcinoma, is disclosed.

Pharmaceutical preparations comprising flutamide

This application relates to treatment of prostatic carcinoma with 4'-nitro-3'-trifluoromethylisobutyranilide.

Antiandrogenic agents and methods for the treatment of androgen

This application relates to certain 4'-substituted and to 3',4'-disubstituted anilides, to methods for their preparation and to methods for their use as antiandrogens. These substituted anilides are useful in the treatment of androgen dependent disease states, such as benign prostatic hypertrophy, hirsutism, acne and the like.

This application relates to certain 4'-substituted and to 3',4'-disubstituted anilides, to methods for their preparation and to methods for their use as anti-androgens.

Substituted anilides as anti-androgens

This application relates to certain 4'-substituted and to 3', 4'-disubstituted anilides, to methods for their preparation and to methods for their use as antiandrogens. These substituted anilides are useful in the treatment of androgen dependent disease states, such as benign prostatic hypertrophy, hirsutism, acne and the like.

Growing community of inventors

Hawthorne, NJ, United States of America

Rudolph O Neri