Baxter Aktiengesellschaft

Other

Baxter International Inc.

Rudolf Kneidinger

Heinz Redl

Walter Fuerst

Douglas L Looker

Sam L Helgerson

Jane P Richards

Elisabeth M Inman

Catalina Wong

A fibrin/fibrinogen binding conjugate for forming a depot for the sustained release of a pharmaceutically active substance from a fibrin clot. The conjugate comprises a fibrin/fibrinogen binding moiety bound to a pharmaceutically active substance either directly or via an intervening substance capturing moiety such as an antibody. The conjugate can also be a recombinant fusion protein comprising a fibrin/fibrinogen binding moiety such as VEGFC-terminal domain fused to a wound-healing substance such as leptin.

Fibrin/fibrinogen-binding conjugate

A fibrin/fibrinogen binding conjugate for forming a depot for the sustained release of a pharmaceutically active substance from a fibrin clot. The conjugate comprises a fibrin/fibrinogen binding moiety bound to a pharmaceutically active substance either directly or via an intervening substance capturing moiety such as an antibody. The conjugate can also be a recombinant fusion protein comprising a fibrin/fibrinogen binding moiety such as VEGF C-terminal domain fused to a wound-healing substance such as leptin.

Fibrin/fibrinogen binding conjugate

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Vienna, Austria

Rudolf Kneidinger