Bayer Aktiengesellschaft

Rudiger Fischer

Mazen Es-Sayed

Graham Sturton

Gabriele Braunlich

Rudolf H Hanko

Mary F Fitzgerald

Trevor S Abram

Michael Sperzel

Rolf Henning

Stephen Richard Tudhope

Wendy J McDonald-Gibson

Klaus-Helmut Mohrs

Burkhard Fugmann

Stephan Schneider

Ulrich Nielsch

Arnel B Concepcion

Barbara Briggs

Steve Tudhope

John-Edward Butler-Ransohoff

Burkhardt Fugmann

Gabriele Br{umlaut Over (a)}unlich

3-Urea-pyridofurans and -pyridothiophenes are prepared by reacting appropriately substituted 3-amino-pyridofurans or -pyridothiophenes with isocyanates or isothiocyanates. The 3-urea-pyridofurans and -pyridothiophenes can be used as active ingredients in medicaments, particularly in medicaments for the treatment of acute and chronic inflammatory processes.

3-Ureido-pyridofurans and -pyridothiophenes for the treatment of inflammatory processes

Heterocyclyclcarbonyl substituted benzofuranyl-ureas are prepared by reacting heterocyclylcarbonyl substituted 3-amino-benzofuranes with appropriate isocyanates or isothiocyanates. The unsubstituted ureas are transferred into substituted ureas by usual methods of substitution. The heterocyclylcarbonyl substituted benzofuranyl-ureas are useful as active ingredients in medicaments particularly for the treatment of acute and chronical inflammatory processes.

Heterocyclylcarbonyl substituted benzofuranyl-ureas

Heterocyclylcarbonyl substituted benzofuranyl- and thiophenyl-alkanecarboxylic acid derivatives are prepared by reacting appropriately substituted hydroxybenzene butanoic acid esters with heterocyclic ketones. The inventive compounds can be used for the preparation of medicaments, particularly of medicaments for the treatment and prevention of acute and chronic inflammatory processes.

Heterocyclylcarbonyl substituted benzofuranyl- and

The inventive Oxalylamino-benzofuran- and benzothienyl-derivatives are prepared by reacting the appropriate amino substituted benzofuranes and benzothiophenes with oxalic acid derivatives. The inventive compounds are suitable for the prevention and treatment of acute and chronic inflammatory processes, particularly of the airways.

Oxalylamino-benzofuran- and benzothienyl-derivatives

The Benzofuranyl- and -thiophenyl-alkane-carboxylic acid derivatives are prepared Tby cyclisation of hydroxy acetophenones and related compounds or by Wittig-reaction of benzofuranyl aldehydes. The compounds can be used to prepared medicaments.

Benzofuranyl-and-thiophenyl-alkanecarboxyclic acid derivatives

Growing community of inventors

Koln, Germany

Rudiger Fischer