Wella Aktiengesellschaft

Rudi Rothlisberger

Friedrich Noser

Wolfgang Hanefeld

Skin treating composition on the basis of compatible carrier and additional compositions with a content of a defined tetrahydro-1,3-thiazine-2,4-dion derivatives as active ingredients for thickening the epidermis. The skin treating compositions are applied 1-2 times daily onto the skin for about 3 to 4 weeks. Due to the thickening of the epidermis they cause a reinforcement of the skin, in particular against sun rays, cold and the contact with noxious environmental substances of all kinds. Moreover, the skin treating compositions are suitable for a prophylactic fighting of the so-called old age skin. An object of the invention are novel tetrahydro-1,3-thiazine-2,4-dion derivative which are active in the aforementioned manner having the formula ##STR1## wherein R denotes H, alkyl, aryl, arylalkyl has substituted arylalkyl or substituted aryl in the aryl portion, R.sup.2 =H is aryl or substituted aryl, R.sup.b =H, denotes aryl or substituted aryl and R.sup.3 =H, represents alkyl or aryl, provided that R.sup.a, R.sup.b and R.sup.c only simultaneously denote H when R denotes a substituted arylalkyl in the aryl portion and R denotes H, but only if R.sup.a =HR.sup.b =aryl and R.sup.c constitute=H.

Tetrahydro-1,3,thiazine-2,4 diones, use thereof and skin treating

Skin treating composition on the basis of compatible carrier and additional compositions with a content of a defined tetrahydro-1,3-thiazine-2,4-dion derivatives as active ingredients for thickening the epidermis. The skin treating compositions are applied 1-2 times daily onto the skin for about 3 to 4 weeks. Due to the thickening of the epidermis they cause a reinforcmenet of the skin, in particular against sun rays, cold and the contact with noxious environmental substances of all kinds. Moreover, the skin treating compositions are suitable for a proplylactic fighting of the so-called old age skin. An object of the invention are novel tetrahydro-1,3-thiazine-2,4-dion derivative which are active in the aforementioned manner having the formula ##STR1## wherein R denotes H, alkyl, aryl, arylalkyl has substituted arylalkyl or substituted aryl in the aryl portion, R.sup.a =H is aryl or substituted aryl, R.sup.b =H, denotes aryl or substituted aryl and R.sup.c -H, represents alkyl or aryl, provided that R.sup.a, R.sup.b and R.sup.c only simultaneously denote H when R denotes a substituted arylalkyl in the aryl portion and R denotes H, but only if R.sup.a =HR.sup.b =aryl and R.sup.c constitute=H.

Tetrahydro-1,3-thiazin-2,4-dione derivatives

3-amino-tetrahydro-1,3-thiazine-2,4-diones, utilization thereof and skin

New 3-carbamoyl- and 3-thiocarbamoyl-tetrahydro-1,3-thiazine-2-thiones are disclosed as skin treatment compositions based upon physiologically-compatible carriers and a content of these compounds as active substance for increasing the skin protection, in particular against sun radiation and contact with environmental substances of all types. The skin treatment compositions are also suitable for prophylactic control of so-called aging skin. The compositions are applied to the skin one or two times daily for about 3-4 weeks.

3-carbamoyl- and 3-thiocarbamoyl-tetrahydro-1,3-thiazine-2-thiones and

Cosmetic agents for the control of head dandruff, containing customary cosmetic carrier substances and additives, and 1 to 5% by weight of salts of at least one biguanide derivative of the general formula ##STR1## wherein m is from 1 to 10 and n is from 1 to 6. Preferred salts include oligohexamethylene biguanide, oligotetramethylene biguanide and 1-methyl biguanide. Also preferred are the hydrochloride salts of biguanide derivatives. The agents may be in the form of shampoos, hair lotions, hair setting preparations, rinses, hair dressing gels and creams, hair oils, powders, or sprays. Customary carrier substances may be an ointment base, a powder, water, alcohol or water-alcohol mixtures. Customary cosmetic additives include resins, emulsifiers, thickeners, hair care substances, coloring agents, perfume oils, solid fillers, and propellants.

Growing community of inventors

Marly, Switzerland

Rudi Rothlisberger