Kosan Biosciences Incorporated

Bristol-myers Squibb Compnay

Corbion Biotech, Inc.

Solazyme Roquette Nutritionals, LLC

Ruchir Desai

Samuel Patinier

John Piechocki

Peter J Licari

Leslie M Norris

Amandine Druon

Marie Le Ruyet

Enrique Baliu

Damien Passé

Timothy Leaf

Rika Regentin

Alexander Redvers Eberlin

Jorge L Galazzo

Greg O Buchanan

Stephen William Watt

Robert Arslanian

Elaine Jennifer Woo

The present invention relates to microalgal food products with acceptable sensory characteristics and methods of producing the food products. The flour can be produced by cultivating microalgal cells of a strain ofunder conditions of acceptable pH and dissolved oxygen to produce a desired amount of lipid. The microalgal cells can be lysed, heat-treated, washed and dried to produce a microalgal flour that can be incorporated into a variety of products.

Microalgal flour

Polymorphs and pharmaceutical formulations of 17-allylamino-17-demethoxygeldanamycin (17-AAG).

17-allylamino-17-demethoxygeldanamycin polymorphs and formulations

During the production of a product compound by fermentation, the concentration of a precursor compound is maintained within a pre-selected concentration range by having an adsorbent resin in contact with the culture medium. The adsorbent resin reversibly adsorbs precursor compound and, as un-adsorbed precursor compound is converted to product compound, adsorbed precursor compound is released from the resin, thus maintaining the concentration of precursor compound within the pre-selected range.

Method of producing a compound by fermentation

A method for the production of a polyketide by fermentation comprising the steps of growing a culture of a polyketide-producing organism at a pH value conducive to cell growth for a time sufficient to generate the producing culture, lowering the pH of the culture to a value conducive to polyketide product stability, continuing the fermentation until a maximal titer of polyketide is achieved, and optionally extracting the polyketide from the culture.

Method for production of polyketides

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Foster City, CA, United States of America

Ruchir Desai