Novo Nordisk A/s

Ruben Archilla

Mattias Ingerslev

Morten Revsgaard Frederiksen

Lars Eilertsen

Christian Plambech

Bo Radmer

Simon Munch Pedersen

Bjoern Gullak Larsen

Morten Soerensen

Soeren Dyring Jensen

Kurt Solgaard

Rasmus Kann Jensen

The present invention concerns a medical injection device for apportioning set doses of a preservative containing liquid drug. The injection device comprises a housing supporting a cartridge containing the preservative containing liquid drug and a needle cannula for transferring the liquid drug from the cartridge and through the skin of a user. Further, a needle shield which is axially movable in relation to the housing is also present. The axially movable shield carries a cleaning reservoir for cleaning at least the tip of the needle cannula between subsequent injections and the cleaning reservoir is preferably filled with preservative containing liquid drug directly from the cartridge upon initiation of the injection device. In order to eliminate any overpressure being built up inside the cleaning reservoir during the filling process, the cleaning reservoir is provided with an outlet configured to be permanently sealed by a user activated operation.

Medical injection device having a sealable cleaning reservoir

The invention relates to a prefilled injection pen for apportioning multiple set doses of a liquid drug. The injection pen comprises a housing assembly with a removable cap rotatable coupled to the housing assembly such that the user has to rotate the removable cap upon mounting and dismounting the removable cap. Rotation of the removable cap initiates a process in which the proximal end of a needle cannula is first inserted into a cartridge permanently embedded in the housing assembly and thereafter moves the cartridge proximally to thereby pump a predetermined amount of the preservative containing liquid drug from the cartridge and into a cleaning chamber carried by an axially movable shield. The needle cannula is mounted in a needle hub which is arranged to follow rotation of the removable cap and guided helically in relation to the housing assembly such that the needle hub is moved proximally upon rotation of the removable cap. Further, the axially movable shield is operated by the needle hub to follow proximal movement of the needle hub such that the distal tip of the needle cannula is maintained inside the cleaning chamber upon axil movement of the needle hub and the needle cannula.

Medical injection device with needle cleaning

The invention relates to a pre-filled injection device for apportioning set dose of a liquid drug. The housing of the pre-filled injection device internally supports a non-replaceable cartridge () having an hollow interior containing a liquid preservative containing drug and externally supporting a removable protective cap (). The piston rod drive system of the injection device comprises a piston rod abutting a plunger provided inside the cartridge. A needle cannula () having a distal part with a distal tip and an opposite proximal part and a lumen there between is insertable into the cartridge. A telescopically movable () shield movable from an extended position covering at least the distal tip of the needle cannula to a retracted position exposing at least the distal tip of the needle cannula is further provided. The telescopically movable shield carries a cleaning chamber () able to contain a quantum of the liquid preservative containing drug for cleaning at least the distal tip of the needle cannula between subsequent injections. The quantum of the liquid preservative containing drug contained in the hollow interior of the cartridge is transferred to the cleaning chamber through the lumen of the needle cannula by moving the cartridge axially in relation to the plunger by use of a transfer assembly.

Medical injection device with telescopically movable needle shield having a cleaning chamber for the needle

Growing community of inventors

Copenhagen, Denmark

Ruben Archilla