E.i. Dupont De Nemours and Company

Roy S Chaleff

Saverio Carl Falco

Narendra S Yadav

John R Bedbrook

Barbara J Mazur

Christopher R Somerville

Thomas B Ray

Cristopher R Somerville

A nucleic acid fragment encoding a herbicide-resistant plant acetolactate synthase protein is disclosed. This nucleic acid fragment contains at least one nucleotide mutation resulting in one amino acid change in one of seven substantially conserved regions of acetolactate synthase amino acid homology. This mutation results in the production of an acetolactate synthase protein which is resistant to sulfonylurea herbicide compounds compared to the wild-type protein. Transformation of herbicide sensitive plants or plant cells with the fragment results in resistance to the herbicide.

Nucleic acid fragment encoding herbicide resistant plant acetolactate

A nucleic acid fragment encoding a herbicide-resistant plant acetolactate synthase protein is disclosed. This nucleic acid fragment contains at least one nucleotide mutation resulting in one amino acid change in one of seven substantially conserved regions of acetolactate synthase amino acid homology. This mutation results in the production of an acetolactate synthase protein which is resistant to sulfonylurea herbicide compounds compared to the wild-type protin. Transformation of herbicide sensitive plants or plant cells with the fragment results in resistance to the herbicide.

Tobacco varieties exhibiting agronomically useful resistance to N-(heterocyclicaminocarbonyl)arylsulfonamide herbicides are produced by tissue culture selection techniques.

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Pennington, NJ, United States of America

Roy S Chaleff