Applera Corporation

Mds Inc.

Roy E Martin

Vincent W Tsang

Timothy E Hutchins

Thomas R Cygan

Richard Gill

Raymond P Burke

In various aspects, the present teaching provide systems for providing sample ions, methods for providing sample ions, and sample support handling mechanisms. The sample support handling mechanisms of the present teachings comprising a sample support transfer mechanism portion and a sample support changing mechanism portion, where the sample support changing mechanism portion is disposed in a vacuum lock chamber. In various embodiments, the sample support handling mechanism facilitates providing consistent positioning of a sample support for subsequent ion generation by MALDI.

Sample handling mechanisms and methods for mass spectrometry

In various embodiments, provided are ion optical assemblies, and systems for mounting and aligning ion optic components. In various embodiments, the present teachings provide ion optical assemblies with features that facilitate the alignment of ion optical elements. In various embodiments, the alignment of the ion optical elements by compressing them with securing members, as described in the present teachings, can simplify the alignment and assembly of ion optical elements. In the present teachings, no torque pattern is required to compress and align the ion optical elements. In various embodiments, the present teachings provide systems for mounting and aligning ion optic components that facilitate their alignment.

Ion optical mounting assemblies

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Worcester, MA, United States of America

Roy E Martin