Lexicon Pharmaceuticals, Inc.

Exxonmobil Technology and Engineering Company

Exxonmobil Research and Engineering Company

California Institute of Technology

Ross Mabon

Bryce Alden Harrison

Allen Wayne Burton

Hilda B Vroman

David Brent Rawlins

Simon Christopher Weston

Spencer David Kimball

Nicole Cathleen Goodwin

Michael A Marella

Kirk D Schmitt

Jason Patrick Healy

Haiming Zhang

Wenxue Wu

Linda C Hsieh-Wilson

Matthew Mangzhu Zhao

Shane Deighton

Arben Jusufi

Karl Gottlieb Strohmaier

Kenneth Gordon Carson

Xiaochun Xu

Yulian Zhang

Joseph M Falkowski

William Joseph Novak

Michael Voronkov

S David Kimball

Dennis Stewart Rice

Brett A Marinelli

Jie Yan

Sarah E Tully

Qiuling Song

Cristal I Gama

Shinya Iimura

Ying Jade Liu

Norris Andrew Whitlock

Joseph Barbosa

Hugh A Burgoon

Hyung Rae Kim

Kanmi Mao

Ashok R Tunoori

Hugh Alfred Burgoon, Jr

Xiaolian Xu

Eugene Terefenko

James Tarver, Jr

William J Novak

Michael Walter Gardyan

Tom Willhammar

Xiaodong Zou

Hongyi Xu

Praveen Pabba

Kristen M Terranova

Kirsten E Schutt

Meghan E Pierson

Michael Victor Voronkov

Qiang Han

Hyung R Kim

Jr Tarver James

Ashok Tunoori

Brett Marinelli

David S Kimball

Bryce A Harrison

Ying Liu

Dennis S Rice

Pabba Praveen

Allen W Burton

Hugh Alfred Burgoon

A method of making a molecular sieve may include: reacting a source selected from the group consisting of: a source of a tetrahedral element in the presence of a structure directing agent (SDA) selected from the group consisting of: Ar-L-Ar, Ar-L-Ar-L-Ar, Ar-L-Ar-L-NR3, and ArAr-L-ArAr, where Aris to a N-containing cationic aromatic ring, Ar is to a non-charged aromatic ring, L is a methylene chain of 3-6 carbon atoms, NR3is to a quaternary ammonium, and ArArand ArAr are a fused aromatic ring structure comprising both a N-containing cationic portion and a non-charged portion, to produce the molecular sieve.

Intramolecular pi-stacking structure directing agents and molecular sieves synthesized therefrom

A method can include heating an aqueous reaction mixture comprising a silicon source and a boron source and/or an aluminum source in the presence of a quaternary structure directing agent to a temperature of at least 75° C. to produce a zeolite. A composition can include a borosilicate zeolite, an aluminosilicate zeolite, or an aluminoborosilicate zeolite having a framework symmetry of C2/m and a unit cell with measurements of a of 3.5 Å to 4.5 Å, b of 20.1 Å to 21.1 Å, c of 15.5 to 16.5 Å, and β of 97° to 98°.

Zeolite syntheses using diquaternary structure directing agents

This disclosure relates to EMM-41 materials, methods for making it, and processes for its use. This disclosure also relates to the structure directing agents used in the methods for making the EMM-41 material as well as the synthesis method used to prepare such structure directing agents.

EMM-41 composition, methods of making and uses thereof

A method can include heating an aqueous reaction mixture comprising a silicon source and a boron source and/or an aluminum source in the presence of a diquaternary structure directing agent to a temperature of at least 75° C. to produce a zeolite. A composition can include a borosilicate zeolite, an aluminosilicate zeolite, or an aluminoborosilicate zeolite having a framework symmetry of C2/m and a unit cell with measurements of a of 3.5 Å to 4.5 Å, b of 20.1 Å to 21.1 Å, c of 15.5 to 16.5 Å, and β of 97° to 98°.

Systems and methods are provided for co-processing of biomass oil with mineral coker feeds in a coking environment. The coking can correspond to any convenient type of coking, such as delayed coking or fluidized coking. The biomass oil can correspond to biomass oil with a molar ratio of oxygen to carbon of 0.24 or less on a dry basis. Such types of biomass oil can be formed from pyrolysis methods such as hydrothermal pyrolysis, and are in contrast to biomass oils formed from pyrolysis methods such as fast pyrolysis. By using a biomass oil with a molar ratio of oxygen to carbon of 0.24 or less, improved yields of light coker gas oil can be achieved in conjunction with a reduction in the yield of heavy coker gas oil.

Co-processing of biomass oil in coker

Provided herein are functionalized branched alcohols comprising a glycosyl group, an ethylene oxide linker and a tail. The ethylene oxide linker comprises one or more units of ethylene oxide. The glycosyl group is a substituent structure of a cyclic monosaccharide. The tail comprises a branched paraffin or isomers thereof, the glycosyl group is attached to the ethylene oxide linker, and the ethylene oxide linker is attached to the tail. In an aspect, the glycosyl group is a substituent structure of glucose, mannose, galactose, sorbose, fructose, xylose, arabinose, ribose, lyxose, lactose, or maltose, or variants thereof. The tail can be a paraffin comprising 9 to 13 carbon atoms.

Functionalized branched alcohols as non-ionic sugar surfactants

Provided herein are novel extended branched alcohols having a lower branching number and improved biodegradability when compared to other branched alcohols. Also provided are novel extended branched ethoxylates having surfactant properties which can be more efficient in reducing surface tension when compared to the ethoxylated form of other branched alcohols. Further provided are novel syntheses of making extended branched alcohols and extended branched ethoxylates.

Surfactant performance through carbon chain extension and lower branching

The disclosure is related to EMM-31 materials, processes, and uses of the same as well as reagents used in the preparation of the EMM-31 materials, process and intermediates for preparing these reagents.

EMM-31 materials and processes and uses thereof

A novel synthetic crystalline material, EMM-28, can be synthesized in the presence of an organic structure directing agent (Q) selected from one or more of the following dications: EMM-28 may be used in organic compound conversion reactions and sorptive processes.

EMM-28, a novel synthetic crystalline material, its preparation and use

Compounds that may be used to inhibit Notum Pectinacetylesterase are described, as well as compositions comprising them, and methods of their use to treat diseases and disorders affecting bone.

4H-thieno[3,2-C]chromene-based inhibitors of Notum Pectinacetylesterase and methods of their use

Sulfanyl-tetrahydropyran-based compounds, pharmaceutical compositions comprising them, and methods of their use for the treatment of diseases and disorders such as diabetes and obesity are disclosed.

Sodium glucose co-transporter inhibitors and methods of their use

Substituted pyrrolo[2,3-d]pyrimidine-based compounds useful as inhibitors of LIM kinase 2 are disclosed. Also disclosed are pharmaceutical compositions comprising the compounds and methods of their use to treat, manage and prevent inflammatory diseases and disorders, cancer, and diseases and disorders of the eye.

Substituted pyrrolo[2,3-d]pyrimidines as LIM kinase 2 inhibitors

Sulfanyl-tetrahydropyran-based compounds and methods of their use

Inhibitors of LIM kinase 2 are disclosed, along with pharmaceutical compositions comprising them and methods of their use. Particular compounds are of the formula: 

LIMK2 inhibitors, compositions comprising them, and methods of their use

Growing community of inventors

Princeton, NJ, United States of America

Ross Mabon