Pioneer Hi-bred International, Inc.

Rosana Melo

Bo Shen

Jingrui Wu

Carl R Simmons

Shane E Abbitt

Mary A Rupe

Shai J Lawit

Carlos M La Rota

Mary J Frank

Genome edited plants, plant cells, seeds and plant parts of maize are provided where expression levels and/or activities of MADS-box transcription factors are modulated to improve one or more agronomic characteristics such as grain yield. Also provided are compositions comprising polynucleotides encoding polypeptides and guide RNAs targeted to endogenous maize MADS-box proteins including for example, targeted site-directed mutagenesis using CRISPR-associated nucleases. Additionally, various methods of employing the polynucleotides and genetic modifications in plants, such as methods for modulating expression level in a maize plant and methods for increasing yield of a maize plant are also provided herein.

Improving agronomic characteristics in maize by modification of endogenous mads box transcription factors

Provided are compositions comprising polynucleotides encoding polypeptides. Also provided are recombinant DNA constructs, plants, plant cells, seed, grain comprising the polynucleotides, and plants, plant cells, seed, grain comprising a genetic modification at a genomic locus encoding a polypeptide. Additionally, various methods of employing the polynucleotides and genetic modifications in plants, such as methods for modulating expression level in a plant and methods for increasing yield of a plant are also provided herein.

MADS box proteins and improving agronomic characteristics in plants

Growing community of inventors

ST. CHARLES, MO, United States of America

Rosana Melo