Cytori Therapeutics, Inc.

Vessix Vascular, Inc.

Boston Scientific Scimed, Inc.

Ronda Elizabeth Schreiber

Marc H Hedrick

John K Fraser

Grace A Carlson

Michael J Schulzki

Bobby Byrnes

Isabella Wulur

Corbett W Stone

Rolfe Tyson Gustus

Susan Riley

Brian D Conn

Meital Mazor

Mike Perry

Michael F Hoey

Michael Perry

Brian Conn

Susan Lynn Riley

Systems and methods are described that are used to separate cells from a wide variety of tissues. In particular, automated systems and methods are described that separate regenerative cells, e.g., stem and/or progenitor cells, from adipose tissue. The systems and methods described herein provide rapid and reliable methods of separating and concentrating regenerative cells suitable for re-infusion into a subject.

Systems for isolating and using clinically safe adipose derived regenerative cells

Regenerative cells present in adipose tissue are used to treat patients, including patients with musculoskeletal diseases or disorders. Methods of treating patients include processing adipose tissue to deliver a concentrated amount of regenerative cells obtained from the adipose tissue to a patient. The methods may be practiced in a closed system so that the stem cells are not exposed to an external environment prior to being administered to a patient. Accordingly, in a preferred method, regenerative cells present in adipose tissue are placed directly into a recipient along with such additives necessary to promote, engender or support a therapeutic musculoskeletal benefit.

Methods of using adipose derived regenerative cells to promote restoration of intevertebral disc

Methods of using regenerative cells in the treatment of cartilage defects

Methods and systems are disclosed for selective drug or fluid delivery in a lumen through a coating or fluid delivery channels. One system includes an elongate catheter having a proximal end and a distal end with an axis therebetween, the catheter having a radially expandable balloon near the distal end and an energy delivery portion proximate the balloon for transmission of energy, a thermally changeable coating having a releasable drug coupled to the balloon, the thermally changeable coating being oriented to be urged against the body tissue when the expandable balloon expands and an energy source operatively coupled to the energy delivery portion configured to energize the energy delivery portion to heat and liquefy the thermally changeable coating to release the drug to the body tissue.

Selective drug delivery in a lumen

Systems and methods for isolating and using clinically safe adipose derived regenerative cells

Systems and methods are disclosed for the treatment of a target tissue by directionally delivering energy and/or bioactive materials to achieve a therapeutic effect. A balloon catheter system having a balloon portion and a plurality of electrodes may be energized to selectively deliver energy, bioactive materials, or a combination thereof to target tissue including tissues disposed about a lumen. The tissue may be targeted by applying energy, making tissue impedance analysis, and further selectively energizing electrodes through the use of an energy source with a controller.

Directional delivery of energy and bioactives

Methods of using regenerative cells in the treatment of musculoskeletal disorders

Automated methods for isolating and using clinically safe adipose derived regenerative cells

Growing community of inventors

Poway, CA, United States of America

Ronda Elizabeth Schreiber