Mallinckrodt Medical, Inc.

Mallinckrodt, Inc.

Ronald W Hagen

Duane L Horton

Mark Edward Boyce

Alexander Lazarevich Klibanov

Donald R Beussink

Apparatus and methods for maintaining the suspension of an agent suspended in a suspending medium in which a container holding the agent is revolved about an axis to create and maintain the suspension and the agent is selectively provided from the container. The agent may be selectively provided from the container while the container is simultaneously or intermittently revolved in a planetary orbit about an axis of rotation generally parallel to an axis of the container for maintaining the suspension. Alternatively, the container may be rotated about its longitudinal axis by a source of rotation to create and maintain the suspension while the agent is provided from the container due to a force imparted by the source of rotation.

Apparatus and method for providing a suspended agent

Methods for packaging a pressure or vacuum sensitive product, such as an ultrasound contrast media comprised of a gas-filled microshpere or microbubble, or sealing such a product in a single-compartment syringe, in a manner that does not utilize pressure or vacuum in the process, are provided.

Methods for packaging a pressure or vacuum sensitive product

A delivery apparatus for delivering various media, such as medical and/or pharmaceutical media or the like, from a delivery device, such as a syringe, in which the delivery pressure of the medium as it is dispensed from the delivery device is automatically maintained and regulated at a preselected level throughout delivery of the medium from the delivery apparatus. In one embodiment, the skin temperature of the patient is also sensed and the pressure of the medium being administered to the patient is further adjusted in response to the sensed skin temperature.

Delivery apparatus with pressure controlled delivery

A pressure monitoring device for indicating to the administrator of an injection to a patient that an excess of force has been exerted on the plunger and thereby the fluids contained within the syringe.

Growing community of inventors

St. Charles, MO, United States of America

Ronald W Hagen