Innocore Technologies B.v.

Ronald Meyboom

Theodorus Adrianus Cornelius Flipsen

Catharina Everdina Hissink

Rob Steendam

Theodorus Adrianus Flipsen

Theodorus Flipsen

The invention relates to a biodegradable multi-block copolymer, comprising at least two hydrolysable segments derived from pre-polymers A and B, which segments are linked by a multi-functional chain-extender and are chosen from the pre-polymers A and B, and triblock copolymers ABA and BAB, wherein the multi-block copolymer is amorphous at physiological (body) conditions. The invention further relates to a process for preparing said copolymer and to its use as a medical implant, a coating for a medical device or a drug delivery vehicle.

Biodegradable multi-block co-polymers

The invention is directed to biodegradable, thermoplastic, phase separated segmented multi-block copolymers. The copolymers of the present invention find use in various biomedical applications as well as in pharmaceutical applications. According to the invention, a biodegradable, phase separated copolymer is provided, comprising segments of a soft prepolymer (A) having a glass transition temperature, Tg, lower than 37&#xb0; C.; and segments of a hard prepolymer (B) having a phase transition temperature, Tm, of 40-100&#xb0; C.

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Haren, Netherlands

Ronald Meyboom