Ethicon, Gmbh

Other

Transmedics, Inc.

Depuy Mitek, Inc.

Transmedic, Inc.

Ronald L Taylor, Jr

Gregory R Whittaker

Harold M Martins

Joan M Sullivan

Waleed H Hassanein

Richard Bringham

Daniel J Mckernan

Tamer I Khayal

Giovanni Cecere

Hossam Algamil

Richard F Wenstrom, Jr

Shawn Thayer Huxel

Steven L Jensen

The disclosure provides, in various embodiments, systems, devices and methods relating to ex-vivo organ care. In certain embodiments, the disclosure relates to maintaining an organ ex-vivo at near physiologic conditions. In certain embodiments, the disclosure relates to testing properties of an ex-vivo heart or an organ care system, adjusting a property of the organ care system in response to certain results of the testing, and re-testing the ex-vivo heart or the organ care system. In certain embodiments, the disclosure relates to synchronizing at least one cycle of a pumping of a perfusion fluid with a state of the ex-vivo heart.

Systems and methods for ex-vivo organ care

An organ care system including a blood product heater that includes a heater inlet, a channel, and a heater outlet, wherein the heater inlet includes an inside cross-sectional area and an inside cross-sectional shape configured to flow a blood product into the blood product heater, wherein the heater outlet comprises an inside cross-sectional area and an inside cross-sectional shape configured to flow the blood product out of the blood product heater, and wherein the channel extends between the heater inlet and the heater outlet and is formed between a first flow channel plate and a second flow channel plate; and a first heater thermally coupled to the first flow channel plate configured to heat the first flow channel plate; and a pump configured to circulate a heated blood product to an organ being preserved.

The invention provides, in various embodiments, systems, devices and methods relating to ex-vivo organ care. In certain embodiments, the invention relates to maintaining an organ ex-vivo at near-physiologic conditions.

A method and apparatus for fixing a ligament in a bone tunnel by cross-pinning the ligament in the bone tunnel.

Method and apparatus for fixing a graft in a bone tunnel

A heart preservation chamber is disclosed which comprises a housing, an inclined trough support surface, and inlet and outlet fluid connections for the major heart blood vessels.

Heart preservation chamber

A method for fixing a portion of a piece of tissue in a bone tunnel comprising the steps of placing the portion of a piece of tissue in the bone tunnel, advancing spaced-apart first and second metal wires though the bone, transversely of the bone tunnel, so as to intersect the bone tunnel and extend into the portion of a piece of tissue, removing one of the wires and replacing the one removed wire with a first rod, and removing the other of the wires and replacing the other removed wire with a second rod, whereby to retain the portion of a piece of tissue in the bone tunnel with the rods.

Method for fixing a graft in a bone tunnel

A method for fixing a bone block in a bone tunnel comprising the steps of placing the bone block in the bone tunnel, advancing spaced-apart first and second metal wires through the bone, transversely of the bone tunnel, so as to intersect the bone block and extend through the bone block, removing one of the wires and replacing the one removed wire with a first absorbable rod, and removing the other of the wires and replacing the other removed wire with a second absorbable rod, whereby to retain the bone block in the bone tunnel with the absorbable rods.

Growing community of inventors

Everett, MA, United States of America

Ronald L Taylor, Jr