The Procter Gamble Company

Norwich Eaton Pharmaceuticals, Inc.

Ronald L Smith

Gerald B Kasting

Timothy P O'Neill

William E Snyder

Eugene G Drust

Sheri Ann Gilbert

Joan B Szkutak

Robert P Charest

Ellen R Massaro

Haruko Mizoguchi

Anne M Carella

Nikhilesh N Singh

Disclosed are oral pharmaceutical vehicle compositions comprising from about 0.05 to about 20% of a water-soluble mucoadhesive.

Oral vehicle compositions

The subject invention involves antitussive pharmaceutical compositions for the peroral administration of dextromethorphan, the composition being at a pH of from about 8 to about 11.

Dextromethorphan antitussive compositions

The subject invention involves compositions and methods of using loperamide and related compounds for treatment of symptoms associated with respiratory diseases.

Use of loperamide and related compounds for treatment of respiratory

Topical pharmaceutical compositions containing a specific 6-amino-1,2-dihydro-1-hydroxy-2-iminopyrimidine component and a penetration-enhancing vehicle are disclosed. The vehicle comprises a binary combination of a C.sub.3 -C.sub.4 diol or C.sub.3 -C.sub.6 triol and isocetyl alcohol polar lipid compound. The vehicle provides marked transepidermal and percutaneous delivery of the iminopyrimidine compound. These compositions, when applied topically, act to stimulate the growth of mammalian hair on the body.

Penetrating topical pharmaceutical compositions

Compositions for the transdermal delivery of buprenorphine comprising a safe and effective amount of buprenorphine in a carrier comprising:

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West Chester, OH, United States of America

Ronald L Smith