Abbott Laboratories Corporation

Abbott Molecular Inc.

Other

Ronald L Marshall

Edward K Pabich

John J Carrino

John A Salituro

Hong Yu

Matthew T Manlove

John D Burczak

Paul A Klonowski

Shiaolan Y Ho

Thomas G Laffler

Suresh M Desai

Isa K Mushahwar

Larry G Birkenmeyer

Thomas P Leary

Jon D Kratochvil

A Scott Muerhoff

Stanley R Bouma

John N Simons

Natalie A Solomon

Bruce J Dille

Cynthia Jou

Hsiang-Yun Y Hu

Laurie A Rinehardt

Joann C Sustachek

David M Henry

Jeffrey L Joseph

The present invention relates to primers and probes that can be used in various assays to detect a new strain of. The invention further provides for the simultaneous detection of other diseases, especially

Primer and probe sequences for detecting chlamydia trachomatis

Polynucleotides useful for detectingand/orin a test sample, kits, a nucleic acid amplification method and detection method including the same.

Polynucleotides for the amplification and detection of chlamydia trachomatis and neisseria gonorrhoeae

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Polynucleotides useful for detectingin a test sample, kits, a nucleic acid amplification method and detection method including the same.

The present invention relates to oligonucleotide probes useful in detecting, e.g. by hybridization or the ligase chain reaction, Chlamydia trachomatis DNA in the presence of other related DNA. The present invention is also directed to methods of detecting Chlamydia trachomatis organisms in a sample using the ligase chain reaction.

Oligonucleotides specific for the MOMP gene sequence and methods for the

Oligonucleotides and methods for the detection of Chlamydia trachomatis

Nucleic oligomer probes useful for detection of HGBV in test samples. Also provided are assays which utilize these probes and test kits which contain these oligomer probes.

Nucleic acid detection of hepatitis GB virus

Amplification of RNA sequences using the ligase chain reaction

Oligonucleotides and methods for the detection of chlamydia trachomatis

Short nucleotide sequences of human papilloma virus useful for the determination of the presence and type of human papilloma virus present in a test sample. The sequences provided can be amplified by polymerase chain reaction or ligase chain reaction. The sequences provided also can be hybridized by standard slot-, dot- or replica-blot procedures. Methods and kits also are provided for the detection of human papilloma virus in a test sample and the determination of the type of human papilloma virus present in the test sample.

Nucleotide sequences useful as type specific probes, PCR primers and LCR

An improved, 'gap filling' embodiment of the Ligase Chain Reaction (LCR) is described. Gap filling LCR is LCR wherein at least one of the probes is recessed so that a gap is formed between the adjacent probes when they are hybridized to target. The gap is filled using polymerase and deoxyribonucleotide triphosphates before ligation of the probes together. There are single and double gap versions, depending on whether one or two probes are recessed and require filling before ligation. The improvement resides in selecting and using target sequences such that only a single type, or two types, of deoxyribonucleotide triphosphate(s) are required to fill double gaps each being 1-10 bases in length, preferably 1-3 bases. Probes having specific sequences are claimed for a number of pathogens.

Amplification of target nucleic acids using gap filling ligase chain

The invention disclosed here is an improvement to a fisherman's float ring whose flotation is normally provided by a donut-shaped inflatable rubber tube. The invention provides the float ring with redundant flotation. This is accomplished by placing a normally deflated secondary tube underneath a seat-supporting fabric which covers the tube. A pressurized gas bottle provides inflating gas for the secondary tube in the event the primary tube is accidentally punctured or deflates. In such case, the secondary tube prevents the float ring from losing its buoyant capability.

Inflatable float ring with redundant flotation means

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Zion, IL, United States of America

Ronald L Marshall