Cepheid Corporation

Syfr, Inc.

Other

Modern Medical Devices

Capheid

Ceoheid

Ronald G Chang

Douglas Bryan Dority

William A McMillan

Farzad Pourahmadi

Kurt Edward Petersen

Jesus Ching

M Allen Northrup

Lee Allan Christel

Steven M Montgomery

Gregory T A Kovacs

Gregory E Mote

Michael T Taylor

Phillip Belgrader

Stanley H Sakai

Robert Allan Yuan

Steven Jay Young

David Swenson

David H Persing

Alan Wortman

Joseph H Smith

Jeffrey S Ross

Shazi S Iqbal

Gregory Edward Mote

Gregory J Kintz

Raymond T Hebert

Reuel Van Atta

Brian M Bliven

James B Ross

Paul Jordan

Jian Ping Zhang

James Jian Quan Wang

Wendy Wong

Kendra Lara Paul

Steve Montgomery

Brian Bliven

Kurt E Peterson

Philip Belgrader

Christel A Lee

Gregory Ta Kovacs

Northrup M Allen

Petersen E Kurt

Douglas P Dority

Gary L Christiansen

Jonathan Siegrist

Stephen M Montgomery

A handling system for high throughput processing of a large volume of biological samples is provided herein. Such systems can include an array support assembly that supports multiple diagnostic assay modules in an array having at least two dimensions, a loader that loads multiple diagnostic assay cartridges within the multiple diagnostic assay modules. The array support assembly can be movable relative the loader to facilitate loading and unloading so as to provide more efficient processing.

Sample processing module array handling system and methods

The invention provides methods and apparatus for carrying out multiple amplification reactions in a single reaction chamber by successive cycles of loading reaction mixture, amplifying, and removing spent reaction mixture in a fluidly closed reaction system. In particular, the present invention allows amplification of a plurality of target polynucleotides from a single sample by carrying out under closed-loop control successive amplifications of different target polynucleotides from different portions of the sample.

Methods and apparatus for sequential amplification reactions

Waste receptacle

Diagnostic assay system

Systems for processing a fluid sample to facilitate analysis with a semiconductor detection chip are provided herein. Such systems can include a sample processing cartridge coupleable with a chip carrier device configured for transport of the processed fluid sample from the sample cartridge. The chip carrier device can include one or more fluid channels extending between fluid-tight couplings attachable to transfer ports of the sample processing cartridge. The chip carrier device can include multiple portions or adapters, including a fluid sample portion, a flowcell portion and a chip carrier. Also provided are methods of preparing and transporting a fluid sample from a sample cartridge into a chip carrier device for analysis with a semiconductor detection chip carried within the chip carrier device.

System, device and methods of sample processing using semiconductor detection chips

Command pod module

Assay processing system

A fluid control and processing system for controlling fluid flow among a plurality of chambers comprises a body including a fluid processing region continuously coupled fluidicly with a fluid displacement region. The fluid displacement region is depressurizable to draw fluid into the fluid displacement region and pressurizable to expel fluid from the fluid displacement region. The body includes at least one external port. The fluid processing region is fluidicly coupled with the at least one external port. The fluid displacement region is fluidicly coupled with at least one external port of the body. The body is adjustable with respect to the plurality of chambers to place the at least one external port selectively in fluidic communication with the plurality of chambers. One or more of the chambers may be a processing chamber which includes two ports configured to selectively engage the at least one external port of the body, and a fluid processing material such as an enrichment material or a depletion material. In some embodiments, one or more chambers may include a separation channel, and an electric field may be applied across the separation channel.

Fluid processing and control

Waste receptacle with lid

Loading track

Growing community of inventors

San Jose, CA, United States of America

Ronald G Chang