Qlt Inc.

University of British Columbia

Other

Valeant Pharmaceuticals International

Retinagenix Therapeutics, Inc.

Novelion Therapeutics Inc.

Qlt, Inc. and

Qlt Phototherapeutices Inc.

The Governors of the University of Alberta

Ronald Erwin Boch

Anna M Richter

David W C Hunt

Julia G Levy

David H Dolphin

Ethan D Sternberg

Ashok Jain

Iman Karmadi

John Robert North

Peter Lutwyche

Robert Gurny

H Andrew Strong

Elizabeth M Waterfield

Guillermo O Simkin

Dev Mitra Ranji Singh

David W Hunt

Suzanne Cadden

Eric Allemann

Andrew Norman Tovey

Yvette Konan

Jean-Marie Houle

Ethan Sternberg

David Wc Hunt

Theresa Mary Allen

Anthony Seng Boey

Dev Mitra Singh

Wendy Monk

Jain Ashok

Andrew N Tovey

Pharmaceutical formulations comprising 9-cis-retinyl esters in a lipid vehicle are described as retinoid replacement therapies for treating retinal degenerations in humans.

Pharmaceutical formulations comprising 9-cis-retinyl esters in a lipid vehicle

Compositions comprising microaggregates containing hydrophobic drugs, as well as methods for their production, are described. Such microaggregates may include micelle structures or combinations thereof with liposomes, and constitute an effective delivery vehicle for a hydrophobic agent. Methods for microaggregate production include the use of preferred lipid compounds and processing conditions favoring the production of small aggregates for improved filter sterilization.

Drug delivery system for hydrophobic drugs

The invention provides nanoparticles containing photosensitizers and their use in the field of photodynamic therapy (PDT). The invention also provides methods for the preparation of such nanoparticles as well as for their sterilization.

Compositions and methods for delivery of photosensitive drugs

Photodynamic therapy (PDT) is used to stimulate and/or restore hair growth in areas of hair loss. Methods and compositions relating to PDT treatment for alopecia are disclosed. In light of PDT use to remove unwanted hair by inactivating or destroying hair follicles or destroying the tissue feeding the hair follicles, such methods and compositions relate to a surprising and unexpected discovery. PDT permits a means to treat conditions relating to hair loss such as androgenic alopecia, alopecia areata and drug-induced alopecia.

Photodynamic therapy for the treatment of hair loss

New compounds useful in photodynamic therapy are of the formula and their 1,4-diene isomersand the metallated and/or labeled and/or conjugated forms thereof

Ethylene glycol esters as photoactive agents

New compounds useful in photodynamic therapy are of the formula ##STR1## and their 1,4-diene isomers and the metallated and/or labeled and/or conjugated forms thereof

Growing community of inventors

Vancouver, Canada

Ronald Erwin Boch