University of Michigan

Michigan Technological University

Altarum Institute

Ronald D Chervin

Joseph W Burns

Benjamin M Segal

Tiffany J Braley

Christopher Roussi

Nikolas Subotic

Provided herein is technology relating to treating sleep apnea and particularly, but not exclusively, to treating sleep apnea with immunotherapeutics and/or anti-inflammatory drugs such as beta-interferons and glatiramer acetate.

Sleep apnea treatment

Methods and systems for diagnosing or assessing rapid eye movement sleep behavior disorder (RBD). Muscle tone or activity variance during rapid eye movement (REM) and non-rapid eye movement (NREM) sleep intervals of a polysomnogram are compared. A threshold based on the NREM data is used to identify a subject-specific threshold for abnormality in the REM variance. A metric that includes the percentage of REM variance exceeding the threshold relates to RBD.

Automated polysomnographic assessment for rapid eye movement sleep behavior disorder

A system and method for determining respiratory cycle-related EEG changes (RCREC) for a subject with sleep-disordered breathing are provided. The method includes receiving an EEG signal from the subject using at least one sensor, and defining at least two respiratory cycle segments within each respiratory cycle. The method further includes determining an EEG power of the EEG signal during each of the at least two respiratory cycle segments, and determining RCREC by calculating a difference between a maximum EEG segment power and a minimum EEG segment power.

System and method for analysis of respiratory cycle-related EEG changes in sleep-disordered breathing

Growing community of inventors

Ann Arbor, MI, United States of America

Ronald D Chervin