Isis Innovation Limited

Oxford University Innovation Limited

Ronald Aurele Roy

Constantin Coussios

Manish Arora

Miklos Gyongy

Nicholas Hawker

Edward Jackson

Natalie Hockham

Jamie Collin

Gail Ter Haar

Sacha D Nandlall

Constantin C Coussios

A method of producing a localized concentration of energy including providing a pocket of gas in a non-gaseous medium and in contact with a surface. The surface includes a depression shaped so as to at least partially receive the pocket of gas. A static pressure is applied to the non-gaseous medium, with an average value greater than atmospheric pressure such that the pocket of gas collapses to form a transverse jet. The surface depression is arranged to receive the transverse jet impact such that at least some of pocket of gas is trapped between the impacting jet and the surface depression. An apparatus for producing a localized concentration of energy is also provided.

Producing a localized concentration of gas between a surface of a depression and an impacting jet that is formed by using static pressure to collapse a gas pocket

Apparatus for locating bubbles in a subject comprises a plurality of pressure wave detectors arranged to operate as passive detectors to generate output signals in response to the receipt of pressure waves generated at a source comprising at least one bubble, and processing means arranged to receive signals from the detectors and to determine from the signals the position of the source.

Mapping and characterization of cavitation activity

A sensing system for sensing the condition of an object comprises a transducer arranged to generate pressure waves directed at the object and detection means, such as a pressure wave detector, arranged to detect cavitation or other processes in the object. The system further comprises processing means arranged to receive detection signals from the detection means, to process the detection signals to measure a signal parameter of the detection signals that varies with a parameter of the object, and may generate a sensor output that varies in response to changes in the signal parameter.

Ultrasound systems

An ultrasound system comprises a transducer, a controller arranged to generate control signals arranged to control the transducer to generate pressure waves directed at a target volume, and sensing means arranged to sense cavitation in the target volume. The controller is arranged to receive sensing signals from the sensing means and to vary the control signals in response to the sensing signals thereby to control the cavitation.

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Brighton, MA, United States of America

Ronald Aurele Roy