Eastman-kodak Company

Ronald A Wellman

Mark E Shafer

John Bruce Findlay

Brent A Burdick

Irvin H Crawford

A multilayer analytical element for the determination of a clinically significant enzyme analyte comprises a photosensitive compound (e.g. a photosensitive dye or dye precursor) and a filter layer containing one or more filter dyes. The filter layer is situated in the element such that incident radiation used to detect a density change resulting from interaction of the analyte and the photosensitive compound passes through the filter layer before it reaches the photosensitive compound. The use of the filter layer inhibits premature changes in the photosensitive compound caused by incident radiation. This element is particularly useful for the determination of creatine kinase or one of its isoenzymes, e.g. creatine kinase-MB.

Analytical element containing photosensitive compound and filter layer

Images are recorded on ultraviolet-light sensitive recording materials employing photographic intermediates which function optically to reflect visible light and transmit ultraviolet light. To give the intermediates the desired optical function, a polyolefin compounded with certain white pigments is included as a sublayer between the paper support sheet and photosensitive layer.

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Rochester, NY, United States of America

Ronald A Wellman