Boston Scientific Scimed, Inc.

Boston Scientific Corporation

Polaroid Corporation

Scimed Life Systems, Inc.

Globus Medical, Inc.

Other

University of Connecticut

Gmedelaware 2 LLC

Prutech Research and Development Partnership Ii

Chemical Fabrics Corporation

Soteira, Inc.

Medi-solve Coatings, Llc.

Charles D. Lennox

Richard A. Noddin

Ronald Sahatjian

Ronald A Sahatjian

James J Barry

Howard G Rogers

Russell A Gaudiana

Arthur R Madenjian

Peter L Dayton

Andrew Sennett

Francisca Tan-Malecki

Bill Little

John Jianhua Chen

Ruth C Bilofsky

John V Hamilton

Bruce S Hamilton

James Coyle

Jeannette S Manello

James Cannon

Liam Farrissey

Dion Gallagher

Maria Palasis

Patrick T Mather

Kurt Geitz

Changdeng Liu

Albert Chin

Kathleen M Miller

John Mugan

Gregory T Sydney

Francisca Tan

Lixiao Wang

David A Ferrera

John E Abele

Andrew J Campbell

Richard A Noddin

Kalpana Kamath

Thomas A Svatek

Peter M Nicholas

Cheryl J Campo

George C Michaels

Charles D Lennox

Jennifer McCrory

Stephen A Griffin

Sheng-Ping Zhong

Thomas Yung-Hui Chien

Eric B Stenzel

Damien Ryan

Robert D Eckert

Arthur L Rosenthal

Martin Bruggeman

Sheng-ping Zhong

Kinh-Luan D Dao

Patrik L&uuml;scher

William R Little

Michael A Savin

Fozan O El-Nounou

Michael Weinreich

Gerard J Bourgeois

Thomas F Kordis

Robert A Sulesky

Martin Bruggemann

Daniel J Kalashian

Albert K Chin

Kurt Amplatz

Gary Jordan

You-Ling Fan

Frederick H Strickler

Robert Burgmeier

Fernando Alvarez De Toledo

Clifford M Liu

Lawrence Marlin

Yiqun Wang

Ismail Guler

Albert C C Chin

Martin J Bruggemann

James Wagner

Ernest J St Pierre

Qing Ge

Robert Boock

Enxin Ma

Sheng Ping Zhong

Patrik Luscher

(Bruce) Yiqun Wang

Robert C Ribbins, Iii

Mark G Steckel

Steven A Schultz

Steve Wu

John Mugen

David W Lodin

David Vafiades

John Chen

Isamail Guller

Timothy J O'SHEA

Systems and methods of delivering and deploying a stent into a curvilinear cavity within a vertebral body or other bony or body structure. In some instances, the system can include an elongate shaft for delivering a self-expanding, cement-directing stent and devices that may be used to perform the steps to deliver and deploy the stent.

Delivery of apparatus and methods for vertebrostening

According to aspects described herein, there is disclosed an improved hot balloon catheter delivery system for shape memory tubular stents. An outer sheath is provided on the delivery system that facilitates stent placement on a balloon during delivery through an endoscope. In one embodiment, the stent may be positioned between radiopaque markers/electrodes and the balloon may be heated. The stent may be prevented from moving proximally relative to the catheter as the delivery system is tracked through the patient's anatomical passageways. The outer sheath may be positioned to ride over the proximal cone of the hot balloon catheter and abut the proximal end of the stent to facilitate proper alignment of the balloon for deployment. Upon deployment of the stent in an appropriate position, the sheath may be pulled away from the stent to expose the proximal cone of the balloon and thereby allow balloon and stent expansion.

Expandable stent delivery system with outer sheath

The invention relates to a cement director for insertion within a vertebral body or other body structure, and related methods of use. An example method includes creating a cavity in a vertebral body, inserting a collapsible mesh structure into the cavity in a collapsed state, wherein the collapsible mesh structure comprises regions of different permeability to a bone cement, inflating a balloon within the collapsible mesh structure to expand the mesh structure, and injecting a bone cement into the mesh structure, wherein the bone cement flows preferentially out of the mesh structure through at least one region of greater permeability.

Balloon expandable cement director and related methods

A radially-expandable stent for implantation in a bodily passageway, being expandable from an initial unexpanded state to an expanded state, having an outer surface with a geometric pattern covering said outer surface to minimize migration after implantation is provided. Also provided is a method of manufacturing such a stent.

Anti-migration features and geometry for a shape memory polymer stent

Delivery of apparatus and methods for vertebrostenting

The present invention generally is directed toward a spinal fixation system whereby a coupling element allows the physician to selectively lock or unlock either the connection between the coupling element and a fastener, such as to allow for repositioning of the coupling element, or the connection between the coupling element and an elongate rod. The locking or unlocking of these connections may be made independently and as desired by the physician.

A medical device includes a balloon catheter having an expandable member, e.g., an inflatable balloon, at its distal end and a stent or other endoprosthesis. The stent is, for example, an apertured tubular member formed of a polymer and is assembled about the balloon. The stent has an initial diameter for delivery into the body and can be expanded to a larger diameter by inflating the balloon.

Implantable medical devices

Disclosed are implantable or insertable medical devices that provide resistance to microbial growth on and in the environment of the device and resistance to microbial adhesion and biofilm formation on the device. In particular, the invention discloses implantable or insertable medical devices that comprise at least one biocompatible matrix polymer region, an antimicrobial agent for providing resistance to microbial growth and a microbial adhesion/biofilm synthesis inhibitor for inhibiting the attachment of microbes and the synthesis and accumulation of biofilm on the surface of the medical device. Also disclosed are methods of manufacturing such devices under conditions that substantially prevent preferential partitioning of any of said bioactive agents to a surface of the biocompatible matrix polymer and substantially prevent chemical modification of said bioactive agents.

Implantable or insertable medical device resistant to microbial growth and biofilm formation

Stabilizing an object in the body of a patient involves the injection of a lower critical solution temperature (LCST) material or other flowable material into the body of the patient so that the material contacts the object. The LCST material or other flowable material then forms a gel in the body such that the object is contained at least partially within the gel and thereby stabilized by the gel such that the object can then be easily fragmented within the body and/or retrieved from the body.

Immobilizing objects in the body

The invention relates to a systems, devices and methods of delivering and deploying a stent into a curvilinear cavity within a vertebral body or other bony or body structure. In some instances, a system can include an elongate shaft for delivering a self-expanding, cement-directing stent. The elongate shaft can include at least one of an inner shaft, an outer shaft, a tubular sheath, a flexible guidewire, and an internal polymer extrusion. A rotational handle can be used to control movement of the elongate shaft. The rotational handle can incorporate one or more pins in slots associated with each of the components (e.g., inner shaft, outer shaft, and tubular sheath), such that upon rotation of the handle, the pins are forced to move in the direction of their respective slots.

Delivery apparatus and methods for vertebrostenting

Implantable or insertable medical devices that provide resistance to microbial growth on and in the environment of the device and resistance to microbial adhesion and biofilm formation on the device. In particular, the implantable or insertable medical devices include at least one biocompatible matrix polymer region, an antimicrobial agent for providing resistance to microbial growth and a microbial adhesion/biofilm synthesis inhibitor for inhibiting the attachment of microbes and the synthesis and accumulation of biofilm on the surface of the medical device. Methods of manufacturing such devices under conditions that substantially prevent preferential partitioning of any of said bioactive agents to a surface of the biocompatible matrix polymer and substantially prevent chemical modification of said bioactive agents.

Growing community of inventors

Lexington, MA, United States of America

Ronald A Sahatjian