Dh Technologies Development Pte. Ltd.

Life Technologies Corporation

Ron Bonner

Yves Le Blanc

Lyle Lorrence Burton

Ignat V Shilov

Sean L Seymour

Alpesh A Patel

The present teachings provide for identification of peptides using small sequence tags to focus computational resources on searching regions of a protein database that are the most likely to yield correct identifications. They allow for the incorporation of modifications and in doing so focuses the search to peptides with a precursor mass match. Additionally, probability or relevance factors can be used to determine peptide hypotheses. Various embodiments are presented that search for peptides when a single precursor is selected or when multiple precursors are simultaneously fragmented.

Method, system, and computer program product for scoring theoretical peptides

Systems and methods for analyzing compounds in a sample. In one embodiment, the present technology is directed towards a method of analyzing a sample, comprising: emitting ions from the sample; selecting the emitted ions for a designated ion; fragmenting the designated ions; scanning for a plurality of designated ion fragments; determining a designated fragment chromatographic trace for each designated ion fragment; and generating a combined chromatographic trace corresponding to a non-linear combination of a plurality of designated fragment chromatographic traces.

Systems and methods for analyzing substances using a mass spectrometer

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Newmarket, Canada

Ron Bonner