Cardiac Pacemakers, Inc.

Boston Scientific Scimed, Inc.

Greatbatch Ltd.

Wilson Greatbatch Technologies, Inc.

Ron A Balczewski

William J Linder

Keith R Maile

Jeffrey Allen Von Arx

Aleksandra Kharam

Mark D Amundson

Brian L Schmidt

William Robert Mass

Jacob M Ludwig

Jeremy J Maniak

Benjamin Keith Stein

Michael John Kane

Bin Mi

Jean M Bobgan

Nicholas J Stessman

Robert S Harguth

Gregory Scott Munson

Michael Wesley Paris

Paul J Huelskamp

Devon N Arnholt

Lance Eric Juffer

John D Hatlestad

Scott Thomas Mazar

Benjamin J Haasl

James Michael English

Jeffrey E Stahmann

Pramodsingh Hirasingh Thakur

Allan Charles Shuros

David L Perschbacher

James O Gilkerson

Moira B Sweeney

Thomas J Harris

James E Blood

William L Zimmer

Ramprasad Vijayagopal

Dan C Goldman

David J Ternes

Gary Thomas Seim

Scott R Vanderlinde

Lawrence David Swanson

Abhijeet V Chavan

David P Stieper

Greg Paul Carpenter

Sarah Melissa Gruba

Cheng Zhang

Thomas Piaget

Daniel Joseph Landherr

Niharika Varanasi

Jason Lahr

Thao N Nguyen

Mark Duane Jansen

Jeff Taylor

Tucker James Nelson

Katherine Hauwiller

Todd W Grotbeck

A medical device includes: a case at least a portion of which functions as a first electrode; a second electrode disposed in a header coupled to the case; a core assembly, the core assembly including operational circuitry enclosed within a core assembly housing, wherein the case includes the core assembly housing; and a battery assembly, the battery assembly including a battery enclosed within a battery housing, where the case further comprises the battery housing; where the operational circuitry is configured to drive a regulated voltage onto the case.

Case driven design for implantable medical device

An implantable medical device may include each of a conductive canister, a printed circuit board assembly (PCBA), and a header. A feedthrough and ferrule couple the interior of the canister, where the PCBA is, to one or more elements contained in the header such as an antenna and/or a port for coupling to a lead. The ferrule may be directly attached to the conductive canister and the electronic circuit board. The electronic circuit board carries an RF transmitter for telemetry purposes, and has an RF ground plane layer therein. The ferrule is capacitively coupled to the RF ground plane the PCBA, and has a size and/or shape relative to the RF ground plane that provides sufficient capacitance to offer an improved RF ground plane path to the conductive canister at a desired telemetry frequency.

Implantable medical device with feedthrough antenna ground structure

Embodiments herein relate to a medical device for treating a cancerous tumor, the medical device having a first lead including a first wire and second wire; a second lead can include a third wire and fourth wire; and a first electrode in electrical communication with the first wire, a second electrode in electrical communication with the second wire, a third electrode in electrical communication with the third wire, and a fourth electrode in electrical communication with the fourth wire. The first and third electrodes form a supply electrode pair configured to deliver one or more electric fields to the cancerous tumor. The second and fourth electrodes form a sensing electrode pair configured to measure an impedance of the cancerous tumor independent of an impedance of the first electrode, the first wire, the third electrode, the third wire, and components in electrical communication therewith. Other embodiments are also included herein.

Electrical stimulation devices for cancer treatment

Embodiments of the present disclosure relate to implantable medical device (IMD) enclosures. In an exemplary embodiment, an IMD comprises: a housing comprising an open end and a header defining a cavity and comprising at least one conduit through a wall of the header, wherein the header is formed from a non-conductive material. Further, the IMD comprises a coupling member comprising a flange, wherein the flange is configured to be received by the open end of the housing and wherein the flange and the open end of the housing at least partially overlap along an axial direction of the IMD when the flange is received by the open end. Additionally, the IMD comprises an electrode arranged on an outer surface of the header and a feedthrough coupled to the electrode and extending through the conduit of the header, wherein the feedthrough is configured to be coupled to internal circuitry housed within the IMD. Further, the IMD comprises a ring forming a hermetic seal between the coupling member and the header.

IMD enclosure formed using dielectric materials incorporating feedthru(s)

Embodiments herein relate to medical devices and methods for using the same to treat cancerous tumors within a bodily tissue. A medical device system is included having at least one electric field generating circuit configured to generate one or more electric fields; control circuitry in communication with the electric field generating circuit, the control circuitry configured to control delivery of the one or more electric fields from the at least one electric field generating circuit; and two or more electrodes to deliver the electric fields to the site of a cancerous tumor within a patient. At least one electrode can be configured to be implanted. At least one electrode can be configured to be external. The control circuitry can cause the electric field generating circuit to generate one or more electric fields at frequencies selected from a range of between 10 kHz to 1 MHz.

Electrical stimulation for cancer treatment with internal and external electrodes

Embodiments herein relate to a method for treating a cancerous tumor located within a subject. The method can include applying one or more electric fields at or near a site of the cancerous tumor, where the cancerous tumor can include a cancerous cell population. The one or more applied electric fields are effective to delay mitosis and cause mitotic synchronization within a proportion of the cancerous cell population. The method can include removing the one or more electric fields to allow mitosis to proceed within the cancerous cell population. The method can include administering a chemotherapeutic agent to the subject after the one or more electric fields have been removed. Other embodiments are also included herein.

Combination electrical and chemotherapeutic treatment of cancer

Embodiments of the present disclosure relate to implantable medical devices. According to an exemplary embodiment, a method for forming an electrode on an implantable medical device (IMD), comprises forming a nonconductive body comprising a well having a bottom surface and at least one side surface extending from the bottom surface. The method further comprises forming a conduit through the bottom surface and inserting the nonconductive body into an opening in an external surface of the IMD. The method also comprises depositing conductive material into the well and coupling the conductive material to a circuit of the IMD via the conduit through the bottom surface of the well.

Implantable medical device including electrodes formed therein

Systems and methods for monitoring patients with respiratory diseases are described. A system may include a sensor circuit configured to sense one or more physiological signals indicative of respiratory sounds, and a spectral analyzer to generate first and second spectral contents at respective first and second frequency bands. The system may produce a respiratory anomaly indicator using the first and second spectral contents, or additionally with other physiological parameters. The system may detect an onset or progression of a target respiratory condition such as asthma or chronic obstructive pulmonary disease using the respiratory anomaly indicator, or to trigger or adjust a therapy.

Systems and methods to detect respiratory diseases using respiratory sounds

Embodiments of the present disclosure relate to implantable medical devices (IMDs). In an exemplary embodiment, an IMD comprises: a housing including a plurality of feedthroughs extending through the housing, a first electrode, a second electrode, and a biocompatible circuit board disposed around an outer surface of the housing. The biocompatible circuit board comprising a plurality of traces, wherein a first trace of the plurality of traces is coupled to the first electrode and a first feedthrough of the plurality of feedthroughs, and a second trace of the plurality of traces is coupled to the first electrode and a second feedthrough of the plurality of feedthroughs.

Implantable medical device having a biocompatible circuit board with embedded electrodes

A medical device includes a case and a core assembly. The core assembly includes operational circuitry enclosed within a core assembly housing. The medical device also includes a battery assembly, which includes a battery enclosed within a battery housing. The case includes the core assembly housing and the battery housing. A first electrode is coupled to, and electrically isolated from, the case; and a second electrode is electrically coupled to the case. The second electrode is electrically coupled to the operational circuitry via a sensing pathway that includes a portion of the case. The battery is electrically coupled to the operational circuitry via an energy supply pathway that includes the portion of the case.

Power noise reduction for an integrated battery

A bridge device includes a housing, a plurality of electrodes exposed outside of the housing such that at least two of the plurality of electrodes can be concurrently placed in contact with a patient's skin. A controller is disposed within the housing. A first communications module is operably coupled to the controller and to the at least two of the plurality of electrodes. The first communications module is configured to allow the controller to communicate with an implantable medical device via at least two of the plurality of electrodes using conducted communication. A second communications module is operably coupled to the controller and is configured to allow the controller to communicate with a remote device external to the patient.

Handheld bridge device for providing a communication bridge between an implanted medical device and a smartphone

Various aspects of the present disclosure are directed toward apparatuses, systems, and methods for supporting components of an implantable medical device. The apparatuses, systems, and methods may include a first electrode and a second electrode and a scaffold assembly configured to support the first electrode and the second electrode.

Implantable medical device having two electrodes in the header

A system includes a pulse generator including a can electrode and a lead couplable to the pulse generator, the lead including a distal coil electrode and a proximal coil electrode, wherein both of the coil electrodes are electrically uncoupled from the can electrode such that a unipolar sensing vector is provided between at least one of the coil electrodes and the can electrode.

Supraventricular tachy sensing vector

Growing community of inventors

Bloomington, MN, United States of America

Ron A Balczewski