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Rolf Zander

Hans Wolf

Hans Uwe Wolf

Werner Lang

Friedrich Mertzlufft

An aqueous solution of gelatin used as a flushing liquid for blood cells, in particular erythrocytes, in order to give no changes in the blood cells or at most slight, quality-impairing changes.

Method for flushing blood cells using gelatin

An apparatus is provided for oxygenating a patient, comprising an oxygen supply means with an oxygen applicator for supplying oxygen via the nose, the oxygen applicator being a closed system, with the applicator affixable about the nose in a tightly-sealable manner so that it supplies pure oxygen solely via the nose in a directed flow, and additionally comprising a one-way valve which can be inserted in substantially sealing-tight manner into the mouth of the patient, the one-way valve opening only upon gas outflow out of the mouth, the closed system at all times having a pressure which is greater than the pressure necessary to open the one-way valve, such that respired air from the patient can escape only through the mouth and no air can escape through the nose.

Apparatus for oxygenating a patient

A sterilizable aqueous solution with substantially physiological values of the pH, bicarbonate concentration and CO.sub.2 partial pressure, as well as with metabolizable anions in the form of two separately stored single solutions, which are combined with one another prior to use and whereof one is a bicarbonate-free, acid solution and the other a bicarbonate-containing, alkaline solution, is characterized in that per liter of the finished solution obtained by combining the two single solutions, the acid single solution contains 7.3 mmole.+-.3% of at least one metabolizable, organic acid and the alkaline single solution 19.1 mmole.+-.3% of alkali bicarbonate and 6.1 mmole.+-.3% of alkali carbonate.

Aqueous solution and the use thereof

In order to simplify the operation for determination of the acid-base status of blood, composed of the values for pH, pCO.sub.2 and the base excess BE, the base excess BE is determined through measurement of the pH-value at a pCO.sub.2 of about 0 mn Hg. The pH-values may be determined photometrically, in which case the indicator solution for measuring the actual blood-pH is an aqueous solution of 40 micromol/l bromthymol blue plus 0.2 g/l sodium dodecylsulfate plus 1% ethanol; and for measurement of the base excess BE is an aqueous solution of 65 micro mol/l naphtholphthalein plus 0.2 g/l sodium dodecylsulfate plus 15% dimethylsulfoxide, which are measured at a wavelength of 635 nm. If desired, one may use a single solution for measuring both actual blood-pH as well as the base excess BE, composed of 16 micromol/l bromthymol blue plus 34 micromol/l naphtholphthalein plus 0.15 g/l sodium dodecylsulfate, which is measured at 615 nm wavelength.

Determination of the acid-base status of blood

In order to simplify the operation for determination of the acid-base status of blood, composed of the values for pH, pCO.sub.2 and the base excess BE, the base excess BE is determined through measurement of the pH-value at a pCO.sub.2 of about 0 mm Hg. The pH-values may be determined photometrically, in which case the indicator solution for measuring the actual blood-pH is an aqueous solution of 40 micromol/l bromthymol blue plus 0.2 g/l sodium dodecylsulfate plus 1% ethanol; and for measurement of the base excess BE is an aqueous solution of 65 micro mol/l naphtholphthalein plus 0.2 g/l sodium dodecylsulfate plus 15% dimethylsulfoxide, which are measured at a wavelength of 635 nm. If desired, one may use a single solution for measuring both actual blood-pH as well as the base excess BE, composed of 16 micromol/l bromthymol blue plus 34 micromol/l naphtholphthalein plus 0.15 g/l sodium dodecylsulfate, which is measured at 615 nm wavelength.

A reagent for photometric determination of the hemoglobin content of blood, which produces a characteristic color upon addition of the blood sample, consisting of an aqueous alkaline solution comprising a water-soluble, non-ionic detergent, whereby all hemoglobin-derivatives occurring in the blood and hemederivatives are converted into a unitary end product having a distinct absorption maximum in the visible spectral range.

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Mainz, Germany

Rolf Zander