Roche Molecular Systems, Inc.

Roche Diagnostics Operations, Inc.

Roche Diagnostics Gmbh

F. Hoffmann-La Roche Ag

Rolf Schneebeli

Geza Burghardt

Renato Belz

Urs Knecht

Alessandro D'Amore

Gottlieb Schacher

Hans-Peter Wahl

Tobias Holenstein

Hans-Rudolf Bachmann

Willem Mulder

Pirow Engelbrecht

Andreas Gisler

Roland Bernet

Christian Marty

Thomas Guggisberg

David Tegerdine

Beat Rene Widmer

Renato Baumann

Markus Troxler

Eric Misselwitz

Reto Schorno

Karl Schmid

Kurt Barmettler

Urs Wittenwiler

Jan Simon Portmann

Nicholas Hastings

Andreas Portmann

Ulrich Schlapfer

David Roger Tegerdine

Jan Portmann

A system for dispensing vessels to an analyzer is disclosed. The system comprises a disc rotatable about an axis and comprising a groove, a drum arranged above and coupled to the disc to rotatable together about the axis, the drum comprising slots arranged along and around the axis, each slot comprising an input interface for stacking vessels in the slot and an output interface for dispensing the vessels, the output interface comprising a retainer, a crank translatable in a linear forwards and backwards direction orthogonal to the axis between a first, second, and third position. The crank comprises a pin for rotating the disc and bringing a slot into a dispensing position upon translation between the first and second position, the crank comprising an actuator pin for actuating the retainer in the dispensing position upon translation of the crank between the second and third position to dispense the vessels.

Vessel dispensing system

A pipetting device () for an apparatus for processing a sample or reagent is disclosed. The pipetting device () comprises a coupling mechanism, wherein the coupling mechanism comprises at least a first coupling unit () adapted to be coupled to a first pipetting tip () and a second coupling unit () adapted to be coupled to a second pipetting tip (), and a selection element () for selectively allowing a coupling of the first coupling unit () to or releasing the first coupling unit () from the first pipetting tip () and for selectively allowing a coupling of the second coupling unit to or releasing the second coupling unit () from the second pipetting tip (). The selection element () is mechanically coupled to the first coupling unit () and the second coupling unit (). Further, an apparatus () for processing a sample or reagent and a method for pipetting a sample or reagent are disclosed.

Pipetting device for an apparatus for processing a sample or reagent, apparatus for processing a sample or reagent and method for pipetting a sample or reagent

A pipetting device () for an apparatus () for processing a sample or reagent is disclosed. The pipetting device () comprises a coupling mechanism (), wherein the coupling mechanism () comprises at least a first coupling unit () adapted to be coupled to a first pipetting tip and a second coupling unit () adapted to be coupled to a second pipetting tip, and a tilt mechanism () for moving the first coupling unit () between an untilted position, in which the first coupling unit () and the second coupling unit () are arranged parallel to one another, and a tilted position, in which the first coupling unit () is tilted relative to the second coupling unit ().

A device, method and system is provided for binding particles for the separation and/or isolation of biological materials. In particular, a container is provided including a suspension of binding particles for the isolation of biological material, inner walls forming an elongate groove at the bottom of said container, and a cover having openings and/or being penetrable for a linear arrangement of multiple pipets or pipet tips, said openings being located above and parallel to said elongate groove.

Suspension container for binding particles for the isolation of biological material

An apparatus for separating magnetic particles from a liquid which contains said particles, said liquid being contained in an elongated vessel () having a length axis (), said vessel being arranged in a vessel holder () with its length axis () in a substantially vertical position, said vessel () having a bottom and a tapered cross-section that diminishes towards the bottom of the vessel and a side wall () which has an outer surface which forms an angle with the length axis () of said vessel (). This apparatus comprises a magnet () having a plane outer surface () and being adapted for being moved by transport means () along a motion path (), said magnet () and said transport means () being so arranged with respect to said vessel () that over a portion of said motion path () said plane outer surface () of said magnet is in contact with a portion of said outer surface of said side wall () of said vessel (), and transport means () for moving said magnet () between a first predetermined position and a second predetermined position along said motion path ().

Apparatus for separating magnetic particles from liquids containing said particles, and an array of vessels suitable for use with such an apparatus

The invention provides for a method of pipetting samples using a pipetting device including more than one pipetting unit. Each of the pipetting units are independently movable in Y and Z directions and includes an upper and a lower frame. Two adjacent pipetting units include a module arranged in a staggered manner in either of the respective upper and lower frames.

Methods for using a pipetting device with independently movable pipette units

A sealing cap for a body fluid container, and a body fluid collection device and system are disclosed. The sealing cap includes an inner cap placeable on an opening in the body fluid container forming a mouth, the inner cap has a shielding member which seals the mouth of the body fluid container, an outer cap resting on the inner cap, the outer cap being movable relative to the inner cap, and a channel member, wherein by a rotational movement the outer cap is movable between an first position in which the channel member is located separated from the shielding member and a second position in which the channel member extends through the shielding member, thereby establishing an open state of the shielding member, and wherein the shielding member returns to a closed state when the outer cap is moved back from the second position to the first position.

Sealing cap for a body fluid container and a blood collection device

A pipetting device is described comprising more than one pipetting unit, wherein said pipetting units are independently movable in Y and Z direction and comprise at least one module arranged in a staggered manner compared to the adjacent pipetting unit.

Pipetting device with independently movable pipette units

The present invention relates to a non-invasive method for surveilling mixing and separation of a suspension in an analytical system using solid phase particles for separation of an analyte by measuring particle distribution with a camera attached to a pipetting device.

Optical surveillance of mixing and separation

A pipette tip and a method for pipetting a congealed blood sample utilizing the pipette tip are disclosed. The pipette tip includes an attachment section configured to be attached to a dispensing device, a liquid containing section configured to receive at least part of an aspired liquid sample, and a liquid aspiration section that is connected to the liquid containing section. The liquid aspiration section has a distal end aspiration opening and at least one further aspiration opening in a side wall.

Pipette tip and a method for pipetting a congealed blood sample utilizing the pipette tip

A new multi-level apparatus is disclosed for high throughput processing of samples. The apparatus does not need interruptions for reloading disposables.

Multi-level diagnostic apparatus with a lift system

This invention involves a thermal cycler capable of performing amplification of nucleic acids. This thermal cycler provides for the fully automatic positioning of its movable lid, which can be placed in two positions. The lid is also suitable for heating a plurality of reaction vessels and for shielding them from light from the environment. In addition, the thermal cycler also includes a thermal block having a plurality of chambers each of which receives the lower part of a reaction vessel. Finally, the thermal cycler has a lid carrier for moving the lid from the first position to the second position and vice versa.

Growing community of inventors

Mettmenstetten, Switzerland

Rolf Schneebeli