Chemspeed Ltd.

Hoffmann-la Roche Inc.

Rolf G&uuml;ller

S&eacute;raphin Munch

Hansj&ouml;rg Tschirky

Philippe Jablonski

Rudolf Schmid

Bruno Lohri

Josef Schr&ouml;er

Thomas Gees

A device for analyzing substances by thin layer chromatography comprises a solvent trough with two solvent channels, wherein two wall plates are mounted in the solvent trough, enabling thin layer plates to be arranged obliquely with respect to the horizontal in the solvent channels. The substance to be analyzed can thus be dropped or applied onto the thin layer plates from above, and solvent can be supplied to the solvent channels from above at a solvent supply point. The upward migration of components of the substance to be analyzed can thus be started without changing the position of the thin layer plate for this purpose.

Device for analyzing substances by means of thin layer chromatography

A device for carrying out a multiplicity of chemical, biochemical or physical processes in parallel has a plurality of switching blocks ( ), to which a multiplicity of reaction vessels ( ) are removably fastened. Liquids, gases and/or solids can be supplied to and/or extracted from the reaction vessels ( ) through the switching blocks ( ). Each switching block ( ) comprises a gas duct plate ( ) and a functional plate ( ) which is arranged so that it can be displaced on it. The gas duct plate ( ) has a multiplicity of through-holes, a gas duct and a multiplicity of gas duct holes extending from the gas duct to the functional plate ( ) and the functional plate ( ) has a multiplicity of through-holes and depressions open to the gas duct plate ( ). Depending on the position of the plates, through-holes, depressions or sealing surfaces of the functional plate ( ) are located opposite to through-holes and gas duct holes of the gas duct plate ( ).

Device for conducting plurality of chemical, biochemical or physical procedures in parallel

An apparatus for providing temperature control and agitation to a plurality of reaction vessels comprises a plurality of elastic receptacles on a block, each receptacle supporting a reaction vessel below its neck, and, a plurality of elastic couplings, each coupling retaining a reaction vessel at its neck section. A flow channel is provided within the block to transfer a liquid temperature control medium to the reaction vessels. The flow channel is routed to each receptacle individually, thereby supplying the medium directly to the corresponding reaction vessel. A shaking arrangement is provided to agitate the reaction vessels by moving the receptacles horizontally relative to the couplings. The greatest deflection of each reaction vessel occurs at its base, while the neck sections are subjected to slight movement.

Device for holding reaction vessels which can be thermally adjusted and agitated

The present invention concerns intermediates useful in and a process for the preparation of a compound of formula 1 or a salt thereof

Growing community of inventors

Herznach, Switzerland

Rolf Güller

Growing community of inventors

Herznach, Switzerland

Rolf G&uuml;ller

Rolf Güller