Amersham Pharmacia Biotech Ab

Amersham Biosciences Ab

Rolf Berglund

Jan Bergstrom

Lennart Soderberg

Makonnen Belew

Jan Bergstr&ouml;m

Lennart S&ouml;derberg

A matrix is disclosed including a core showing a system of micropores and a surface in which the micropore system has openings. The characterizing feature is that the surface is coated with a polymer (I) having such a large molecular weight that it cannot penetrate into the micropores.

Matrices for separation and separation exploiting said matrices

Process for, in layers of a porous matrix, exhibiting the groups A, introducing a functionality using a reagent I, introducing the functionality by a reaction with the groups A. The characterizing feature is that the matrix is contacted with a functional deficiency of reagent I and that conditions and reagent I are chosen so that the reaction between reagent I and the groups A is more rapid than diffusion of reagent I in the matrix.

Process for introducing a functionality

Process for chromatographic separation of peptides and nucleic acid, and

Growing community of inventors

Uppsala, Sweden

Rolf Berglund