Roche Diagnostics Operations, Inc.

Roche Diagnostics Gmbh

F. Hoffmann-la Roche Ag

Roland Hutter

Rik Harbers

Andreas Calatzis

Friedrich Karl Ackermann

Jean-Pierre Bolliger

Theresa Kitcoff

Patrick Sascha Labud

Roland Stoeckli

A reagent management system is disclosed comprising a reagent container section for receiving reagent containers and a reagent reconstitution device for reconstituting dry, or lyophilized, reagents or concentrated reagents in reagent containers in order to carry out in-vitro diagnostic tests with the reconstituted reagents. A controller is programmed to instruct the reagent reconstitution device to automatically reconstitute an initial volume of a selected reagent type in reagent containers. The initial volume is calculated based on an open container stability time (OCS) of the reconstituted reagent type for each reagent container and on a number of tests to be carried out within the OCS of the reconstituted reagent type. A reagent container for use by the reagent management system and methods of automatically reconstituting a dry, or lyophilized reagent, or a concentrated liquid reagent in a reagent container to carry out an in-vitro diagnostic test with the reagent are disclosed.

Reagent management system

A pipetting unit and a method of using the pipetting unit for pipetting a volume Vof test liquid for carrying out an in vitro diagnostic test are presented. The method comprises dipping a nozzle of a pipetting unit into a test liquid and aspirating a volume Vof the test liquid larger than the volume Vrequired for carrying out the test. The method further comprises dipping the pipetting unit into a wash liquid and dispensing a volume Vequal or smaller than Vminus Vof the test liquid into the wash liquid. The method further comprises dipping the pipetting unit into a reaction liquid and dispensing the volume Vof test liquid required for the test.

Pipetting unit and method of pipetting a test liquid

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Zug, Switzerland

Roland Hutter