Stamicarbon B.v.

Stamicarbon B.v. Licensing Subsidary of Dsm

Roland E Van Der Stoel

Cornelis G Van De Moesdijk

Petrus H Janssen

Marcel A Bosma

Alkylpyrimidines are dealkylated to the corresponding pyrimidines by contacting with an oxidation catalyst containing one or more oxides of at least one of the elements of the group consisting of Bi, Mo and V in the presence of water and oxygen in the gas phase at a temperature of 300.degree.-450.degree. C.

Process for preparing pyrimidine

Process for preparing pyrimidine by reacting in the gas phase 1,3-diaminopropane with a C.sub.1 reagent in the presence of an excess of methanol and/or carbon monoxide and of a metallic catalyst, wherein the reaction is carried out in the presence of a palladium catalyst promoted with an alkali metal and subsequently from the resulting reaction mixture pyrimidine is recovered.

Process for the preparation of 2-pyridone in the gas phase comprising contacting 6-methyl-2-pyridone with a metallic dealkylation catalyst in the presence of water at a temperature of 200.degree.-500.degree. C.

Process for the preparation of pyridone-2 by demethylation

Pyridone-2 compounds are prepared by reacting an oxoalkanecarboxylic acid having as general formula ##STR1## where R.sub.2 and R.sub.3 represent hydrogen or an alkyl group having 1-4 C atoms, or an ester of such an acid in the gas phase with an amine compound R.sub.1 NH.sub.2,

Process for the preparation of a pyridone-2

Disclosed is a process for preparing a lactam which consists essentially in the reductive amination in the gas phase of an oxoalkane carboxylic acid having the formula ##STR1## or an alkyl ester thereof, wherein R is an alkyl group having from 1 to 4 carbon atoms and n varies from 2 to 3, and wherein the reaction is carried out:

Process for the preparation of a lactam

A process is described for the catalytic gas phase reduction of 4-oxoalkanenitriles to form 2-alkylpyrroles in high yields and conversions.

Process for the preparation of a 2-alkylpyrrole

Indole, and/or methyl-substituted indoles are described as prepared from the corresponding 2-(cyanomethyl)cyclohexanone starting material through a catalytic reaction in the presence of hydrogen, using a metal, or metal compound, of Group VIII or Group Ib of the Periodic Table. The reaction is carried out at an elevated temperature at high conversion to yield the corresponding indole and (in some cases) tetra- or hexahydroindoles.

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Buchten, Netherlands

Roland E Van Der Stoel