Janssen Vaccines & Prevention B.v.

Bavarian Nordic A/s

Janssen Sciences Ireland Unlimited Company

Roland Christian Zahn

Soumitra Roy

Maria Grazia Pau

Jerôme Hubertina Henricus Victor Custers

Benoit Christophe Stephan Callendret

Markus Kalla

Frank Wegmann

Jean-Marc Edmond Fernand Marie Neefs

Daniel Boden

Helen Horton

Gijs Hardenberg

Methods of inducing an immune response against human immunodeficiency virus (HIV) are described. In particular, methods of inducing an immune response against HIV by co-locally administering an immunogenically effective amount of an isolated HIV envelope (Env) polypeptide and an immunogenically effective amount of an adenovirus vector encoding an HIV antigen, e.g., Env antigen are described. The isolated HIV Env polypeptide and adenovirus vector can be administered in a single composition or in separate compositions, in which the composition or compositions do not contain an adjuvant.

Method of inducing an immune response against human immunodeficiency virus by co-localized administration of vaccine components

Provided herein are Modified Vaccinia Ankara (MVA) vectors and adenovirus vectors encoding HBV antigens. Also provided are methods of enhancing an immune response in a human subject by utilizing the MVA and adenovirus vectors encoding HBV antigens in a prime/boost regimen to the enhance the immune response in the human subject.

Methods and compositions for inducing an immune response against Hepatitis B Virus (HBV)

Compositions, vaccines and methods using adenovirus vectors for priming and boosting vaccinations for inducing protective immunity against a Marburg virus infection are described.

Methods and compositions for inducing protective immunity against a Marburg virus infection

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Rijnsburg, Netherlands

Roland Christian Zahn