Lubrizol Advanced Materials, Inc.

Other

Roger W Day

Umit G Makal

Hua Zhang

Richard Woofter

Bryce W Steinmetz

Kiara L Smith

Qiwei Lu

Feina Cao

Kiara Smith

The disclosed technology provides thermoplastic polyurethane compositions having antimicrobial properties while still maintaining good physical properties and good non-fouling properties, methods of making the same, and articles, including medical devices, made from such compositions. The disclosed technology includes a process of making an antimicrobial polymer composition, where the process includes mixing an antimicrobial additive into a base polymer and further includes mixing in a non-fouling additive, where the antimicrobial additive is chemically held in the composition and the antimicrobial and non-fouling additives do not negatively impact each other's effectiveness.

Antimicrobial, non-thrombogenic polymer composition

The disclosed technology provides thermoplastic polyurethane compositions having non-leaching antimicrobial properties while still maintaining good physical properties, methods of making the same, and articles, including medical devices, made from such compositions. The disclosed technology includes a process of making an antimicrobial polymer composition, where the process includes mixing an antimicrobial additive into a polymeric material; wherein said polymeric material comprises a polymeric backbone made up of urethane linkages derived from a polyisocyanate and a polyol; and wherein said mixing occurs under conditions that result in the breaking of a minority of said urethane bonds resulting in reactive isocyanate groups; and wherein two or more of said reactive isocyanate groups react with said antimicrobial additive to covalently bond said antimicrobial additive into the polymeric backbone of said polymeric material; resulting in an antimicrobial polymer composition.

Antimicrobial thermoplastic polyuethanes

A biocidally active polymer composition formed from an oligomeric or polymeric additive and a thermoplastic polyurethane polymer is disclosed. The biocidally active polymer may further include a non-fouling and/or non-thrombogenic polymer. The biocidally active polymer provides biocidally active properties, and may also provide non-fouling and/or non-thrombogenic properties. The composition is particularly useful in articles and materials for medical applications.

Biocidally active polymer compositions

A surface-modified polymer composition formed from an oligomeric or polymeric additive and a base polymer is disclosed. The surface-modified polymer provides non-fouling and/or non-thrombogenic properties. The composition is particularly useful in articles and materials for medical applications.

Surface modified polymer compositions

The invention provides a bioabsorbable blend of (i) a polymer component comprising polylactic acid (PLA), polyglycolic acid (PGA), a copolymer of PLA and PGA, or any combination thereof and (ii) thermoplastic polyurethane (TPU) tailored to a medical application, and a process for making the same. In some embodiments, the TPU comprises units derived from a diol chain extender, a diisocyanate, and a polyol formulated to provide a set biodegradation rate in combination with at least one physical property. The blend of the invention provides useful materials for medical applications that have the individual benefits of polylactic acid and TPU while moderating each material's typical limitations.

Bioabsorbable polymer blends

The present invention relates to novel thermoplastic polyurethane (TPU) compositions that have crystalline chain ends. The TPU compositions of the invention can provide improved resiliency, lower surface free energy, and/or reduced stickiness, while maintaining other desirable physical properties. The present invention also provides the described TPU compositions that are further grafted with vinyl alkoxysilane moieties allowing for crosslinked networks of the TPU compositions. The present invention also provides plasticizer-free, very soft TPU compositions without the processing difficulties often associated with such materials. The invention further provides means of reducing the surface tension of a TPU composition which can allow for improved blend compositions, and means of crosslinking the described TPU compositions.

Thermoplastic polyurethanes with crystalline chain ends

The present invention relates to a melt processable copolyetheramide made by reacting (a) one or more segments of polyamide hard blocks derived from a lactam-terminated diisocyanate and a lactam monomer, and (b) one or more segments of polyether soft blocks derived from a polyether diol. The invention further provides for methods of making said copolyetheramide, including a continuous extruder method of production.

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Solon, OH, United States of America

Roger W Day