Roche Diagnostics Operations, Inc.

Roche Molecular Systems, Inc.

Roche Diagnostics Gmbh

F. Hoffmann-la Roche Ag

Roger Sandoz

Emad Sarofim

Carlo S Effenhauser

Goran Savatic

Edwin Oosterbroek

Michael Glauser

Rijk Edwin Oosterbroek

Daniel Mueller

Geza Burghardt

Oliver Gutmann

Frank Ulrich Schubert

Hans-Rudolf Bachmann

Renato Baumann

Daniel Müller

Hans-Peter Wahl

Michael Heinrich

Tomas Gruebl

An acceleration sensitive indicator for indicating a centrifugation status of a biological sample, a sample container comprising the indicator, a centrifuge for centrifuging samples and an analytical system for analyzing centrifuged samples are disclosed. The indicator comprises at least one closed chamber, formed between two opposite surfaces, that comprises an indication zone that comprises at least two fluid transfer zones or at least one particle transfer zone. The at least one fluid transfer zone comprises a solid carrier phase and a fluid stabilized in the solid carrier phase or at least one non-stabilized non-Newtonian fluid having thixotropic and/or shear thinning properties. The at least one particle transfer zone comprises a particle stabilizing fluid comprising stabilized dispersed particles. The fluid or particles have a distribution with respect to the indication zone changeable upon application of a g-force above a threshold value, the change of distribution indicating the centrifugation status.

Acceleration sensitive indicator

A micro fluidic device comprises a laminate structure, comprising a plurality of individual layers. At least one layer comprises a micro fluidic channel structure and at least on one side of said layer a further layer is arranged comprising a three-dimensional (3D) micro structure such that the 3D micro structure is influencing a flow characteristic of a fluid within the micro fluidic channel structure.

Fluidic device containing 3D structures

A device and a method for the adjustment of a temperature of a liquid which is contained in one or more sample vessels are specified, a control unit and a temperature adjustment unit being provided, which acts on the liquid contained in the sample vessels. Furthermore, the control unit is operatively connected to the temperature adjustment unit. The liquid to be analyzed contains absorption elements in order to accelerate the temperature adjustment in the liquid to be analyzed.

Device and method for the adjustment of a temperature of a liquid

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Rotkreuz, Switzerland

Roger Sandoz