L'oreal

Roger Rozot

Maria Dalko

Christophe Boulle

Bruno Bernard

Dominique Bernard

Alexandre Cavezza

Benoit Muller

Jean-François Michelet

Agnes Thomas-Collignon

Agnès Thomas-Collignon

The present invention relates to the use of a compound, suitable for modulating the interaction between first and second partner proteins, or between homologues, mutants, or fragments of said proteins, said first and second proteins being SASPase and filaggrin-2, or FLG2, as an active agent for treating and/or preventing aesthetic defects in the skin, and/or in the appendages thereof, linked to an imbalance in the differentiation and/or proliferation of the cells of the epidermis.

Process for treating an individual with an esthetic defect of skin by modulating SASPase FLG2 complex

The invention relates to the use of a compound of formula (I), or salts thereof, as a preserving agent, in particular in a cosmetic, dermatological or pharmaceutical composition: in which R1 and R2 represent H, methyl, ethyl, phenyl or benzyl. The invention also relates to a method of preserving a cosmetic, dermatological or pharmaceutical composition, consisting in incorporating said compound of formula (I) therein; and also to the compositions thus obtained.

Use of benzyloxy-ethylamine derivatives as a preservative, preservation method, and compositions

The present invention relates to a cosmetic process for treating wrinkled skin, in particular the skin of the face and/or of the forehead, through a dermo-decontracting effect, comprising the topical application to said skin of a composition comprising, in a physiologically acceptable medium, at least one piperidine derivative chosen from the compounds of formula (I). These compounds make it possible to combat expression wrinkles according to a mechanism of dermo-decontraction. 

Use of piperidine derivatives as dermo-decontracting agents

A regime/regimen (and compositions therefor) for inducing and/or stimulating the growth of keratinous fibers and/or slowing the loss and/or increasing the density thereof, notably human hair and/or eyelashes, entails administering to a mammalian subject in need of such treatment, for such period of time as required to elicit the desired effect, a thus effective amount of at least one 2-alkylideneaminooxyacetamide compound having the formula (I): 

Care/makeup compositions comprising a 2-alkylideneaminooxyacetamide compound for stimulating the growth of the hair or eyelashes and/or slowing loss thereof

The invention relates to a cosmetic composition containing at least one 15-hydroxy-prostaglandin dehydrogenase inhibitor and cosmetically acceptable excipients. It also relates to a method of cosmetic treatment for promoting the growth and/or preventing or delaying the loss of hair, and the use of a 15-hydroxyprostaglandin dehydrogenase inhibitor for the preparation of a composition intended for controlling hair loss and/or for promoting hair regrowth.

Cosmetic composition, method of cosmetic treatment and preparation of a composition for promoting the growth and/or preventing or delaying the loss of hair

Heterocyclic compounds useful for stimulating/inducing the growth of keratinous fibers, notably human hair/eyelashes, and/or slowing the loss of same, have the following structural formula (I) or salt thereof: in which Hy is a heterocycle of 4 to 7 atoms, optionally comprising carbonyl/thiocarbonyl functional groups, and G is O, S or NH.

Heterocyclic compound for stimulating or inducing the growth of the hair or eyelashes and/or slowing down their loss, composition comprising it and its uses

Growing community of inventors

Lagny/Marne, France

Roger Rozot