General Dynamics Advanced Information Systems, Inc.

Brightspec, Inc.

Roger Reynolds

Justin L Neill

Bouvard Hosticka

Kathy Terlesky

Matt Muckle

Charles Daitch

Stephen C Francesconi

Eric J Van Gieson

Molecular rotational resonance (MRR) spectroscopy is a structurally-specific, high-resolution spectroscopy technique that can provide accurate reaction process data with finer time resolution than existing techniques. It is the only analytical technique that can make online chiral composition measurements. This makes it especially useful for online reaction monitoring, which is done today by manually pulling off samples and measuring samples offline and takes 3-4 hours per measurement. Conversely, an MRR spectrometer can resolve isomers in about 10 minutes when fed with a low-volatility sampling interface that connects directly to the reaction line. The sampling interface measures a precise sample of the reaction solution, boils off the solvent to concentrate the analyte, volatilizes the analyte, and injects the volatilized analyte into the MRR spectrometer's measurement chamber for an MRR measurement. The sample concentration and volatilization happen quickly and without any extra sample preparation.

Methods and apparatus for low-volatility sampling

The present invention relates to a collection device for a substance, and methods related to collecting thereof.

Portable sampling device for airborne biological particles

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Charlottesville, VA, United States of America

Roger Reynolds