G.d. Searle & Company

Roger M Upton

Kevin Robert Lawson

Albert A Jaxa-Chamiec

George J Ellames

Peter L Myers

The present invention relates to a class of novel chloro-substituted ketone imidazole derivatives. The invention further relates to pharmaceutical compositions containing such compounds and to the use of such compounds and compositions as anti-anaerobic agents.

Chloro-substituted ketone imidazole derivatives

This disclosure relates to a compound of the formula: ##STR1## or a pharmaceutically acceptable salt thereof, wherein R.sup.1 and R.sup.2 are independently selected from the class consisting of hydrogen, halo, C.sub.1 -C.sub.6 alkyl, and C.sub.1 -C.sub.6 alkoxy;

Substituted 1H-pyrimido[1,2-a-]-pyrido[3,4-e]pyrazine 6 oxides

This disclosure relates to a novel class of substituted quinoxaline derivatives. The disclosure further relates to pharmaceutical compositions containing such compounds and to the use of such compounds and compositions as anti-anaerobic agents.

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High Wycombe, United Kingdom

Roger M Upton