Ge Healthcare Bio-sciences Ab

Ge Healthcare Limited

Cytiva Sweden Ab

Roger Lundqvist

Dan Hermansson

Johan Lilja

Klaus Gebauer

Sven Wounder

Stefan D'Argy

Nils Lennart Thurfjell

Lars Mattsson

Bjorn A Johansson

Key Hyckenberg

Mikael Berg

Gunnar Malmquist

Helena Skoglar

Linda Mathiasson

Sara Sendabo

Dan Andersson

Nils Lenaart Thurf Jell

Javier Jurio

Mikael Carlsten

Johan Axel Lilja

Mikael Johan Helmer Eugen Berg

Lars Henning Ivar Mattsson

Björn A Johansson

The present invention relates to a method for optimizing a bioprocess purification system comprising a bioreactor configured to provide a harvest comprising a target composition, and a purification process arranged downstream the bioreactor and being configured for purification of the harvest to produce a target product having a desired characteristics. The method comprising: a) detecting () at least one quality attribute indicative of characteristics of the target product in a downstream process, b) identifying () correlations between the at least one quality attribute measured in the downstream process and parameters to control a cell culture process in the bioreactor, and c) controlling () the cell culture process to meet the desired characteristics based on the identified correlations, whereby the target characteristics is within a p re-determined range.

Method in bioprocess purification system

An adaptive template image for registering a PET or a SPECT image includes a template image model including variability of values for each voxel in a template image according to one or more control parameters.

Methods of spatial normalization of positron emission tomography images

An implementation of SSP using variable depth for the vectors extending normal to the surface voxels of the brain so as to avoid white matter uptake extraction is provided. The implementation also provides the possibility to compare SSP for an individual amyloid imaging agent image to a SSP normal database and allows for 3D visualization of SSP information.

Variable-depth stereotactic surface projections

The invention relates to a multi-component part transducer assembly for determining the pressure of a fluid of interest. One part of the assembly comprises a reusable transducer, another part a disposable component comprising a flexible membrane which is in pressure connection with the fluid of interest, and another part comprises a locking component for securing the reusable and disposable parts together.

Multi-component part transducer assembly and a method for determining the pressure of a fluid using the transducer

Tie-bar for a chromatography column

A pinch valve is adapted to hold at least one flexible tube in a tube holding room () and comprises a plunger () adapted to protrude into the tube holding room and pinch the tube against an opposite side wall () thereof. The plunger () is controllable to be positioned in at least two different positions, an open position where the tube in the tube holding room () is not pinched, and a pinching position where the tube is pinched between the plunger () and the opposing wall (). The pinch valve further comprises a tube retaining means () adapted to prevent the tube from escaping from the tube holding room (), especially when the plunger () is in the open position, and which can be pivoted into at least two different positions, a non locking position used during insertion of a tube into the tube holding room (), and a locking position for retaining a tube inside the tube holding room () even when the plunger is in an open position.

Pinch valve

Chromatography column

Growing community of inventors

Alunda, Sweden

Roger Lundqvist