Convatec Limited

Apimed Medical Honey Limited

Acordis Speciality Fibres Limited

Roger Bray

Champa Patel

Philip Roy Caskey

Phillip Roy Caskey

An antibacterial wound dressing is based on or derived from gel-forming fibers such as carboxymethyl cellulose or alginate fibers having silver ions linked thereto at some but not all of the exchangeable sites such that the distribution of silver ions over the exchangeable sites is substantially uniform. The silvered fibers for the wound dressing can be prepared by contacting an assembly of precursor gel-forming fibers having exchangeable sites under conditions which do not cause irreversible gelling of the fibers with an amount of a solution containing silver ions so as to link silver ions at some but not all of the exchangeable sites, the whole of the assembly of precursor gel-forming fibers being contacted essentially simultaneously with the entire solution containing silver ions.

Antibacterial wound dressing

An antibacterial wound dressing is based on, or derived from, gel-forming fibres such as carboxymethyl cellulose or alginate fibres having silver ions linked thereto at some but not all of the exchangeable sites such that the distribution of silver ions over the exchangeable sites is substantially uniform. The silvered fibres for the wound dressing can be prepared by contacting an assembly of precursor gel-forming fibres having exchangeable sites under conditions which do not cause irreversible gelling of the fibres with an amount of a solution containing silver ions so as to link silver ions at some but not all of the exchangeable sites, the whole of the assembly of precursor gel-forming fibres being contacted essentially simultaneously with the entire solution containing silver ions.

A wound dressing comprises a wound-contacting layer composed of a mixture of honey and a moisture-absorbing agent; a water-permeable fabric backing layer; and an intermediate layer comprising water-permeable fabric impregnated with a mixture of honey and a moisture-absorbing agent.

Wound dressings

Wound dressings in the form of a body-shaped component are composed of body-shaped cellulosic fabric which has been carboxymethylated at the woundcontacting surface. The body-shaped component composed of a fabric comprising a cellulosic material is subjected to a carboxymethylation process to carboxymethylate the cellulosic material at the wound-contacting surface.

Carboxymethylated cellulosic wound dressing

Carboxymethylated cellulosic articles having degree of substitution in the range from 0.12 to 0.35 and in which the carboxymethyl groups are believed to be predominantly within the amorphous regions to the exclusion of the crystalline regions have usefully non-adherent properties as wound dressings. Such wound dressings may be made by carboxymethylating a cellulose fabric so that its absorbency is little greater after carboxymethylation than beforehand and the degree of substitution is as stated above. Carboxymethylation can be carried out by contacting cellulose II fibers or other articles with a solution containing sodium hydroxide, sodium chloroacetate, water and ethanol. The solution may contain from 4 to 8 percent by weight sodium hydroxide and from 50 to 60 percent by weight water (including water in the fibre) or the weight ratio of sodium hydroxide to water (including water in the article) may be from 0.095 to 0.115 and the weight ratio of cellulose in the article to water (including water in the article) may be from 0.22 to 0.28.

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Nuneaton, United Kingdom

Roger Bray