Empire Technology Development LLC

Coaptus Medical Corporation

Roger Alan Sahm

Yansong Gu

Josef Peter Klein

Floyd Brian Karp

Robert S Schwartz

Robert A Van Tassel

Robert Lawrence Barry

David C Auth

Bryan A Kinsella

Joseph E Eichinger

Luisa Mayorga Szott

Block co-polymers including a hydrophilic block and a hydrophobic poly(amino acid) block which further includes dihydroxyphenyl moieties are provided, as well as methods of making and using the same. Such block copolymers may be used to prepare biocompatible adhesives which display good adhesives properties in aqueous environments, including in in vivo applications.

Biocompatible adhesive polymers

A block co-polymer includes a water soluble carrier block; an amino acid-based or acrylic acid-based block; and the amino acid-based or acrylic acid-based block includes a fluorinated alkyl group or a fluorinated alkylene glycol group.

Fluorinated block co-polymers

The present invention provides for therapeutic treatment methods, devices, and systems for the partial or complete closure or occlusion of a patent foramen ovale ('PFO'). In particular, various methods, devices, and systems for joining or welding tissues, in order to therapeutically close a PFO are described. In yet another aspect of the invention, various methods, devices, and systems for the penetration of the interatrial septum enabling left atrial access are also provided.

Transseptal closure of a patent foramen ovale and other cardiac defects

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Snohomish, WA, United States of America

Roger Alan Sahm