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Louisiana State University and Agricultural & Mechanical College

Rodney E Shackelford

Christopher Kevil

Suming Wang

The presently claimed invention is related to compositions and methods for treating HS related diseases comprising administering a pharmacologically effective amount of pharmaceutical composition containing a first therapeutic, wherein the first therapeutic includes one of an ATR kinase inhibitor and an ATR kinase promotor. According to further embodiments the HS related disease is one of cancer, cardiovascular disease, acute inflammation, chronic inflammation, and neurological disease.

Methods and therapeutics to regulate hydrogen sulfide bioavailability

This invention relates to the methods and pharmaceutical compositions for treating diseases or disorders associated with oxidative stress and/or genomic instability. In particular, the invention relates to methods for treating ataxia-telangeictasia (AT) and such disease states by administering a therapeutically effective amount of a chelating agent to increase genomic stability and/or decrease oxidative stress.

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Shreveport, LA, United States of America

Rodney E Shackelford