Rox Medical, Inc.

Sub-q, Incorporated

Intersect Ent Gmbh

Boston Scientific Scimed, Inc.

Usgi Medical, Inc.

Scimed Life Systems, Inc.

Micro Therapeutics, Inc.

Sinexus, Inc.

Galt Laboratories, Inc.

Advanced Surgical Intervention, Inc.

Other

Edwards Lifesciences Corporation

Boston Scientific Corporation

Covidien LP

Cardiovascular Dynamics, Inc.

Rodney A Brenneman

J Christopher Flaherty

Donald J Eaton

William L Pintauro

Barry N Gellman

David J Sauvageau

Armand A Morin

Andrew H Cragg

Rodney Appell

Mark Philip Ashby

Mary Lynn Moran

Brad M Kellerman

Jay Alan Lenker

Vahid Saadat

Richard Christian Ewers

Cang C Lam

Thomas R Tice

Dean A Schaefer

Patrick A Arensdorf

David B Downie

Danielle L Biggs

Eugene G Chen

Sheila K Wallin

Mario Maciel

Chris A Rothe

Kenneth J Michlitsch

George B Wallace

Eduardo Chi Sing

Boris Reydel

Thomas J Berryman

Robert R Greene

Robert Rosenbluth

Peter Gregory Davis

Douglas S Cali

Andrew M Cragg

Brent Seybold

Brad Kellerman

Eugene C Chen

Peter Davis

Dean Schaefer

George Robert Greene

Minh Tran

Danielle L Clay

Edward A McDonald

Rich C Ewers

Paul Degarate

Saadat Vahid

Peter Balmforth

Donald Kolehmalnen

Patrick A Maley

Paul Davidovich

Christopher J Flaherty

Mary L Moran

William Pintauro

Edwardo Chi Sing

The invention provides biodegradable implants for treating sinusitis. The biodegradable implants have a size, shape, density, viscosity, and/or mucoadhesiveness that prevents them from being substantially cleared by the mucociliary lining of the sinuses during the intended treatment period. The biodegradable implants include a sustained release therapeutic, e.g., an antibiotic, a steroidal anti-inflammatory agent, or both. The biodegradable implants may take various forms, such as rods, pellets, beads, strips, or microparticles, and may be delivered into a sinus in various pharmaceutically acceptable carriers.

Sinus delivery of sustained release therapeutics

A shunt rivet for implantation between a first body space and a second body space in a patient, such as to treat chronic obstructive pulmonary disease.

Device and method for establishing an artificial arterio-venous fistula

Described here are paranasal sinus devices for treating paranasal sinus conditions. The devices include a cavity member, ostial member, and nasal portion. One or more of the cavity member, ostial member, and nasal portion may deliver an active agent for sustained release to treat the paranasal sinus condition. Exemplary paranasal sinus conditions are sinus inflammation due to functional endoscopic sinus surgery (FESS) and rhinosinusitis.

Device and methods for treating paranasal sinus conditions

A shunt rivet for implantation in the aorta and inferior vena cava to treat chronic obstructive pulmonary disease, and a method of treating chronic obstructive pulmonary disease.

Provided is a method of treating cardiac arrhythmia in a patient. The method comprises selecting a patient suffering from a cardiac arrhythmia and creating a flow pathway between a first vascular location and a second vascular location. The first vascular location comprises a source of arterial blood and the second vascular location comprises a source of venous blood. Systems and devices for creating a flow pathway are also provided.

Methods, systems and devices for treating cardiac arrhythmias

Provided is a method of treating arterial hypertension in a patient. The method comprises selecting a patient suffering from arterial hypertension and creating a flow pathway between a first vascular location and a second vascular location. The first vascular location comprises a source of arterial blood and the second vascular location comprises a source of venous blood. The method causes a reduction in diastolic pressure and a reduction in systolic pressure; and the reduction in diastolic pressure is to an extent at least approximating the reduction in systolic pressure. Systems and devices for creating a flow pathway are also provided.

Methods, systems and devices for treating hypertension

A shunt rivet for implantation in the aorta and inferior vena cava to treat chronic obstructive pulmonary disease, and a method of treating chronic obstructive pulmonary disease. The shunt rivet may be formed to have a central section, a proximal clinch section, and a distal clinch section each having one or more clinch members. These one or more clinch members may be trained to be resiliently biased to bend radially outwardly from the central section.

Devices, systems and methods are disclosed for the formation of an arteriovenous fistula in the limb of the patient. Embodiments include a device for the creation, modification and maintenance of a fistula that includes an integral fistula creation assembly near its distal end that passes through the skin of the patient, through a first vessel such as an artery, and into a second vessel such as a vein. The fistula creation assembly preferably includes an anastomotic implant that is placed within the fistula to maintain long-term blood flow therethrough. The devices, systems and methods can be used to treat patients with one or more numerous ailments including chronic obstructive pulmonary disease, congestive heart failure, hypertension, hypotension, respiratory failure, pulmonary arterial hypertension, lung fibrosis and adult respiratory distress syndrome.

Devices, systems and methods for creation of peripherally located fistula

Devices, systems and methods are disclosed for the formation of an arteriovenous fistula in the limb of the patient. Embodiments include an apparatus for the creation, modification and maintenance of a fistula, including the modification of an existing dialysis fistula; and a method of supplying oxygenated blood to the venous circulation of a patient. A kit of anastomotic implants is described which supports a broad base of patient anatomies and fistula locations. The devices, systems and methods can be used to treat patients with one or more numerous ailments including chronic obstructive pulmonary disease, congestive heart failure, hypertension, hypotension, respiratory failure, pulmonary arterial hypertension, lung fibrosis and adult respiratory distress syndrome.

Devices, systems, and methods for peripheral arteriovenous fistula creation

A method for treatment of COPD, hypertension, and left ventricular hypertrophy, and chronic hypoxia including creation of an artificial arterio-venous fistula and installation of a flow mediating device proximate the fistula. The flow mediating device is operated to limit flow as medically indicated to provide the optimum amount of bypass flow.

Method of treating COPD with artificial arterio-venous fistula and flow mediating systems

Growing community of inventors

San Juan Capistrano, CA, United States of America

Rodney A Brenneman