Other

Universiteit Twente

Nanomed Diagnostics Bv

Roderik Adriaan Kraaijenhagen

Albert Van Den Berg

Loes Irene Segerink

Herbert Michael Pinedo

Coenrad Karel Van Kalken

Jacobus Adrianus Nieuwenhuijzen

Renske Daniëla Maria Steenbergen

Willem Frederik Rurup

Idris Bahce

Geert Kazemier

Edwin Thomas Carlen

Johan Bomer

Songyue Chen

The invention provides in vitro methods of determining whether an individual has a pre-cancer or cancer comprising determining the presence or absence of one or more methylation markers of a methylation marker set in a urine sample of said individual; and determining whether the individual has pre-cancer or cancer based on the detection of the presence or absence of said one or more methylation markers in the urine sample, wherein the presence of said one or more methylation markers indicates that the individual has pre-cancer or cancer. The invention further provides methods for typing pre-cancer or cancer based on the the presence or absence of one or more methylation markers of a methylation marker set in a urine sample.

Detection of cancer in urine

The invention relates to a capsule or chip or sensor comprising a marker/detector and signalling device/method associated with the development of a medical condition/disease and to its use. This In Situ Lab On a Chip Signalling device (ISLOGS device) is used for detecting a medical condition/disease in situ or in vivo (inside the body), for example by swallowing it for testing in the digestive tract or by putting it into the vagina, mouth or nose. All reactions takes place in the body and when the test result is positive the device will notify the subject by colorizing the tested body fluid or biomaterial (for example faeces, urine or saliva) or the device itself. The detection is made outside of the body when the biomaterial or ISLOCS device has left the body.

Device for detecting a medical condition or disease

A method and computer installation for communicating with one or more other computer installations with a processor, and memory with data and instructions stored therein so that the processor can execute a predetermined program. The program enables the processor to receive the following data: anamnesis data for a client; physical/diagnostic data for the client; data on diagnostic methods; and use of medication and treatment methods with regard to predetermined diseases. The program enables the processor to calculate, and incorporate in a report, the following: the risk of the client acquiring one of the predetermined diseases, harbouring such a disease or having such a disease; data with regard to a possible prevention programme for the client to prevent the one of the predetermined diseases; and data with regard to any medication to combat the one of the predetermined diseases that may be harboured or existing.

Computer installation for establishing a diagnosis

Growing community of inventors

Amstelveen, Netherlands

Roderik Adriaan Kraaijenhagen