Merck Patent Gmbh

Roberto Ognibene

Guenter Moddelmog

Finn Bauer

Thorsten Wedel

Dieter Lubda

Gudrun Birk

Daniela Kleinwaechter

Hans-Leonhard Ohrem

Sandra Erika Bernhardt

Melanie Mechthild Breidung

The present invention relates to a novel directly compressible matrix for the production of tablets which disintegrate rapidly in the presence of moisture, in particular in the mouth.

Direct injection moldable and rapidly disintegrating tablet matrix

The present invention relates to premixes for the production of active compound-containing tablets which comprise polyvinyl alcohols (PVAs). The invention also relates to active compound-containing tablets which comprise a corresponding premix.

Pulverulent, directly compressible polyvinyl alcohol grades

The present invention relates to novel pharmaceutical formulations which have controlled, delayed release of active ingredient, and to a process for the preparation of such formulations. The invention additionally relates to the use of these novel pharmaceutical administration forms as medicaments for the treatment of diseases which require delayed release of the active ingredient, such as hypertension, or asthmatic diseases.

Formulation having controlled, delayed release of active ingredient

The present invention relates to a directly compressible composition for the production of tablets which comprise fine-grained polyvinyl alcohols (PVAs) and fine-grained microcrystalline celluloses (MCCs) in a co-mixture. The present invention also relates to the use of this mixture and to a process for the preparation thereof.

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Darmstadt, Germany

Roberto Ognibene