Sigma-tau Industrie Farmaceutiche Riunite S.p.a.

Roberto Cozzolino

Maria Ornella Tinti

Fabio Giannessi

Domenico Misiti

Orlando Ghirardi

Carlo Scolastico

Orally or parenterally administrable pharmaceutical compositions in unit dosage form comprise from about 100 to about 500 mg of one of the compounds of formula (I). ##STR1## wherein R is selected from: 2-(N,N-diisopropyl)aminoethyl,

Pyroglutamic acid derivatives as enhancers of learning processes and

1,2,3,4-tetrahydronaphthlamines of formula (1) ##STR1## wherein R is H or OCH.sub.3 ; ##STR2## is either at 1 or 2 position R.sub.1 is H;

Derivatives of 1,2,3,4-tetrahydronaphtylamine endowed with nootropic

Pharmaceutical compositions for enhancing the process of learning and memory are disclosed, that contain as active principle a 3-amino-.epsilon.-caprolactam of formula (1) ##STR1## Wherein R is selected from the group consisting of hydrogen, formyl and acetyl. Orally or parenterally administrable pharmaceutical compositions in unit dosage form comprise from about 100 to about 500 mg of a compound of formula (1).

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Rome, Italy

Roberto Cozzolino