Biomolecular Products, Inc.

Children's Hospital Los Angeles

Biomet Microfixation, LLC

Robert Travis McKee

Walter Allen Shaw

Stephen W Burgess

David W Yesair

Shawn David Roman

Barry J Maurer

Charles Patrick Reynolds

Saddy Rodolfo Garcia

Ryan Nicholas Luby

Bradley James Winterroth

C Patrick Reynolds

Derek Sean Lewis

Shon David Steger

Larry Colgan

Barry James Maurer

Apparatus and methods of fixating bone include repairing or remodeling a hard tissue defect with a composite bone structure. The composite bone structure includes at least two hard tissues or bones and a scaffold material fixed together by an adhesive component. The apparatus and methods include positioning the hard tissues/bones, conforming the scaffold material to at least a portion of a surface of the hard tissues/bones, contacting the adhesive component with the hard tissues/bones and the scaffold material, and changing the material state of the adhesive component to another material state at which the adhesive component fixes together the hard tissues/bones and the scaffold material, thereby forming a composite bone structure having a desired rigidity.

Apparatus and methods of fixating bone

Methods for hydrolyzing solid ungranulated lysophosphatidylcholine with phospholipase Aare provided. Also disclosed are methods for making a lipid matrix of lysophosphatidylcholine, monoglyceride and fatty acid, and lipid matrices of particular structure.

Modifications of solid 3-sn-phosphoglycerides

A driver assembly may include a fastener and a driver. The fastener may have a head with upper and lower surfaces. An engagement portion may be located in the upper surface proximate a perimeter portion thereof. A shank may extend from the lower surface of the head and a breakaway portion may extend from the upper surface of the head. The driver may include a shaft having a body with a first end having a fastener-engaging portion. The fastener-engaging portion may have an outer driving geometry engaged with the engagement portion of the fastener when in an engaged position. The first end may further include an opening therein. The opening may receive at least a portion of the breakaway portion when in the engaged position.

Driver assembly and fastener apparatus

The present invention provides an edible composition for oral delivery of an active agent such as a retinide. The composition comprises, in the form of a dry flowable powder: (a) an active agent such as a retinide; (b) lipid matrix composition; (c) optionally sweetener; (d) flour. Compositions of the invention may be administered per se or mixed with a solid or liquid food carrier, for direct oral consumption by a subject or administration through a feeding tube.

Oral compositions of fenretinide having increased bioavailability and methods of using the same

The present invention provides an edible composition for oral delivery of an active agent such as paclitaxel or a retinide. The composition comprises, in the form of a dry flowable powder: (a) an active agent such as a retinide; (b) lipid matrix composition; (c) optionally sweetener; (d) flour. Compositions of the invention may be administered per se or mixed with a solid or liquid food carrier, for direct oral consumption by a subject or administration through a feeding tube.

Oral pharmaceutical compositions and methods of using the same

Modification of solid 3-sn-phosphoglycerides

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Jacksonville, FL, United States of America

Robert Travis McKee